A Single Nucleotide Polymorphism in the 5′ Untranslated Region of the EGF Gene Is Associated with Occurrence and Malignant Progression of Gastric Cancer

Y Hamai, S Matsumura, K Matsusaki, Y Kitadai… - Pathobiology, 2005 - karger.com
… region (UTR) of the EGF gene and that peripheral blood … significantly lower levels of EGF
than cells from individuals with the … defined EGF polymorphism may be associated with genetic

Association between EGF, TGF‐β1, VEGF gene polymorphism and colorectal cancer

G Wu, T Hasenberg, R Magdeburg… - World journal of …, 2009 - Wiley Online Library
… Single nucleotide polymorphisms (SNPs) are the most … on EGF gene expression in normal
colon in colorectal cancer patients [12]. We hypothesized that the EGF 61 gene polymorphism

Association between functional polymorphism in EGF gene and malignant melanoma

M Shahbazi, V Pravica, N Nasreen, H Fakhoury… - The Lancet, 2002 - thelancet.com
… We hypothesised that EGF is a candidate gene for … of the EGF gene to determine whether
any polymorphisms exist in … of the identified polymorphism by measuring EGF production; and …

No Association Between EGF Gene Polymorphism and Gastric Cancer

Y Goto, T Ando, H Goto, N Hamajima - Cancer Epidemiology Biomarkers & …, 2005 - AACR
… We investigated a single nucleotide polymorphism at exon 1 of EGF, named rs4444903 in
NCI dbSNP, in 454 Japanese subjects undergoing a health checkup and 202 patients with …

Single nucleotide polymorphisms of genes for EGF, TGF-β and TNF-α in patients with pancreatic carcinoma

L Zhang, G Wu, F Herrle… - Cancer genomics & …, 2012 - cgp.iiarjournals.org
EGF and EGF-R may be a potential prognostic factor for pancreatic cancer (43). It will be a
topic of future studies to show if EGFEGF -61 * AG and the TNF-A -308 * AG polymorphisms

A Functional Polymorphism in the EGF Gene Is Found with Increased Frequency in Glioblastoma Multiforme Patients and Is Associated with More Aggressive …

DA Bhowmick, Z Zhuang, SD Wait, RJ Weil - Cancer research, 2004 - AACR
… the relevance of this single nucleotide polymorphism in patients with … a single nucleotide
polymorphism in the 5′UTR of EGF is significantly correlated with increased expression of EGF

[HTML][HTML] Epidermal growth factor gene (EGF) polymorphism and risk of melanocytic neoplasia

MR James, NK Hayward, T Dumenil… - Journal of investigative …, 2004 - Elsevier
nucleotide polymorphism (SNP) in the 5′ untranslated region (5′UTR) of the epidermal
growth factor (EGF) gene … that the nucleotide 61 polymorphism of the EGF gene predisposes to …

Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer

KLG Spindler, JN Nielsen, D Ornskov… - Acta …, 2007 - Taylor & Francis
… Recently a single nucleotide polymorphism in the EGF gene has been identified (EGF A61G…
importance and the functional influence on EGF gene expression levels in colorectal cancer (…

EGF gene polymorphism and the risk of incident primary melanoma

KL Amend, JT Elder, LP Tomsho, JD Bonner… - Cancer Research, 2004 - AACR
… Overexpression of the epidermal growth factor (EGF) pathway has been … single nucleotide
polymorphism (G to A) in the EGF gene where the G allele was associated with increased EGF

A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma

BKA Dayyeh, M Yang, BC Fuchs, DL Karl, S Yamada… - Gastroenterology, 2011 - Elsevier
… In conclusion, we have shown that single-nucleotide polymorphism 61*G in the EGF gene
correlates with the risk of HCC independent of several known or purported clinical risk factors …