Management of venous thromboembolism in morbid obesity with rivaroxaban or warfarin

P Weaver, TH Ng, T Breeden… - Annals of …, 2022 - journals.sagepub.com
… to investigate individual DOAC safety and effectiveness against … safety of rivaroxaban
versus warfarin for the treatment of VTE in morbidly obese patients with a weight >120 kg or BMI >…

Effectiveness and safety of direct oral anticoagulants versus warfarin in obese patients with acute venous thromboembolism

JC Coons, L Albert, A Bejjani… - … : The Journal of Human …, 2020 - Wiley Online Library
… of 40 kg/m 2 or higher who newly initiated apixaban, rivaroxaban, or … obese patients had
a VTE recurrence rate at 12 months that was not significantly different from those patients who …

Rivaroxaban plus aspirin in obese and overweight patients with vascular disease in the COMPASS trial

TJ Guzik, C Ramasundarahettige, N Pogosova… - Journal of the American …, 2021 - jacc.org
… All patients enrolled in the COMPASS trial received the same dose of rivaroxaban despite
a broad range of BMI and body weights (5). Obesity has been shown to influence the …

[HTML][HTML] Efficacy, safety, and exposure of apixaban in patients with high body weight or obesity and venous thromboembolism: insights from AMPLIFY

AT Cohen, S Pan, W Byon, BS Ilyas, T Taylor… - Advances in Therapy, 2021 - Springer
… and 0.63, respectively) in rivaroxaban-treated patients. Major bleeding events were
numerically lower in rivaroxaban-treated patients across all body weight and BMI categories [18]. …

[HTML][HTML] Real life behaviour of direct oral anticoagulants in patients with nonvalvular atrial fibrillation and morbid obesity

B Navarro-Almenzar, JJ Cerezo-Manchado… - IJC Heart & …, 2021 - Elsevier
… The most frequently prescribed drug in this group was rivaroxaban (40%). … patients with
morbid obesity included in the ROCKET trial. In our study, none of the morbidly obese patients

Efficacy and Safety of Direct Oral Anticoagulants (DOACs) in Morbidly Obese Patients

C Kalani, EA Henry, T Alexander, G Udeani, S Surani - Chest, 2018 - journal.chestnet.org
obese patients. We sought to examine the efficacy and safety of the DOACs, apixaban,
dabigatran, and rivaroxaban… bleeding events in patients with either a body-mass index (BMI) over …

[HTML][HTML] Comparative effectiveness and safety of rivaroxaban and warfarin among nonvalvular atrial fibrillation (NVAF) patients with obesity and polypharmacy in the …

JS Berger, F Laliberté, A Kharat, D Lejeune… - Advances in …, 2021 - Springer
… of NVAF patients with obesity and polypharmacy in the US. We hypothesized that
rivaroxaban would be an effective and safe treatment option for NVAF patients with obesity and …

[HTML][HTML] Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH

K Martin, J Beyer‐Westendorf, BL Davidson… - Journal of Thrombosis …, 2016 - Elsevier
safety of DOACs in obese patients are limited. We reviewed the available data on the use of
DOACs in obese patients … the effects of obesity on the pharmacokinetics of rivaroxaban. The …

Morbidly obese patient on rivaroxaban presents with recurrent upper extremity deep vein thrombosis: a case report

SLT Jennings, KNP Manh… - Journal of pharmacy …, 2020 - journals.sagepub.com
… validate rivaroxaban use in extreme BW and BMI patients. In this article, we report a morbidly
obese patient with recurrent upper extremity DVT (UEDVT) while taking rivaroxaban for …

[HTML][HTML] Successful use of rivaroxaban achieving therapeutic anti-factor xa levels in a morbidly obese patient with acute intermediate-high risk pulmonary embolism

K Dah, M Porres-Aguilar, AD Rosa… - Jornal Vascular …, 2023 - SciELO Brasil
obese individuals remains uncertain. We present the case of an extremely obese patient (BMI
>… (DVT) successfully treated with rivaroxaban with demonstrable therapeutic anti-Xa levels …