Obesity and cancer: the role of dysfunctional adipose tissue

RCM Van Kruijsdijk, E Van Der Wall… - Cancer epidemiology …, 2009 - AACR
… We propose that adipose tissue dysfunction has a prominent role in cancer pathogenesis …
linking obesity to cancer have been postulated. We propose that dysfunctional adipose tissue

Common mechanisms of dysfunctional adipose tissue and obesity‐related cancers

P Matafome, D Santos‐Silva… - … research and reviews, 2013 - Wiley Online Library
adipose tissue accumulation, and most of the features of hypertrophic adipose tissue are
observed in cancer … pathological adipose tissue alterations that may contribute to cancer

[HTML][HTML] Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach

PL Prieto-Hontoria, P Pérez-Matute… - … et Biophysica Acta (BBA …, 2011 - Elsevier
obesity typically leads to insulin and leptin resistance and a shift to dysfunctional adipose
tissue… These conditions cause metabolic dysregulation with elevated circulating fatty acids and …

The role of dysfunctional adipose tissue in pancreatic cancer: A molecular perspective

D Brocco, R Florio, L De Lellis, S Veschi… - Cancers, 2020 - mdpi.com
… surrounding dying or dead adipocytes) of inflamed adipose depots, represent the most
abundant cell population in obese dysfunctional adipose tissue and the leading source of pro-…

Targeting obesity-related adipose tissue dysfunction to prevent cancer development and progression

A Gucalp, NM Iyengar, CA Hudis, AJ Dannenberg - Seminars in oncology, 2016 - Elsevier
… with obesity. Therefore, this review focuses on the underlying biologic mechanisms associated
with impaired adipose tissue function in the context of cancer … impact of obesity on cancer

[HTML][HTML] Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation

R Divella, R De Luca, I Abbate, E Naglieri… - … of Cancer, 2016 - ncbi.nlm.nih.gov
tumors such as breast, colon, liver and prostate, obesityDysfunctional adipose tissue in
obesity releases a disturbed profile … Therefore, adipose tissue hypoxia might contribute to cancer

Adipose tissue dysfunction in obesity

M Blüher - Experimental and clinical endocrinology & diabetes, 2009 - thieme-connect.com
… of obesity. This review focuses on the current knowledge about mechanisms … adipose tissue
causing or maintaining adipose tissue dysfunction in obesity and potentially linking obesity

Adipose tissue inflammation and metabolic dysfunction in obesity

T Kawai, MV Autieri, R Scalia - American Journal of …, 2021 - journals.physiology.org
… Despite its low-grade nature, adipose tissue inflammation negatively impacts remote
organ … of obesity. The aim of this review is to broadly present an overview of adipose tissue

Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer

AB Crujeiras, A Díaz-Lagares, MC Carreira… - Free radical …, 2013 - Taylor & Francis
… Because of the widespread epidemics of obesity and T2DM, it was proposed that a better
understanding of the relationship between dysfunctional adipose tissue and T2DM offers the …

Adipose tissue dysfunction and its effects on tumor metabolism

J Diedrich, HC Gusky, I Podgorski - Hormone molecular biology and …, 2015 - degruyter.com
… VAT from other adipose tissues in studies investigating the impact of obesity and metabolic
disorders on skeletal health, because using the central obesity measures continues to lead to …