Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
… % of the patients in this study received erlotinib as a fourth-line or subsequent treatment,
the results from this study were similar to those of clinical studies. We deduce that erlotinib is …

EGFR mutation frequency and effectiveness of erlotinib: a prospective observational study in Danish patients with non-small cell lung cancer

B Weber, H Hager, BS Sorensen, T McCulloch… - Lung Cancer, 2014 - Elsevier
… routine in patients with adenocarcinoma, and as a consequence seven EGFR … patients in
our study (1.5%) received erlotinib as first-line treatment. All patients were treated with erlotinib

Erlotinib for elderly patients with non‑small‑cell lung cancer: Subset analysis from a population‑based observational study by the Ibaraki Thoracic Integrative …

K Kurishima, H Satoh, T Kaburagi… - Molecular and …, 2013 - spandidos-publications.com
patients receiving erlotinib treatment, the outcomes of the elderly (≥75 years) and younger
(<75 years) groups of patients were similar in our population‑based observational study. …

… predictive factors of erlotinib in a non-small cell lung cancer unselected European population previously treated: a retrospective, observational, multicentric study

P Cioffi, V Marotta, C Fanizza… - Journal of Oncology …, 2013 - journals.sagepub.com
… A serious limit of our observational study is that it was not … of the Erlotinib registration in
Italy 9 ) to March 2010 (date of the Gefitinib registration in Italy 9 ), patients treated with erlotinib

Real-life effectiveness of erlotinib as second-line treatment of stage IIIB/IV squamous non-small cell lung cancer: results of the PEPiTA observational study

I Monnet, C Audigier-Valette, N Girard, A Vergnenègre… - Lung Cancer, 2016 - Elsevier
erlotinib use in squamous NSCLC. This article reports the results of an observational study
(PEPiTA: Patient … of use of second-line erlotinib in patients with stage IIIB/IV squamous …

[HTML][HTML] … erlotinib in non-small cell lung cancer patients undergoing dose reduction and those with a low body surface area: A population-based observational study by …

M Inagaki, Y Shinohara… - Molecular and …, 2016 - spandidos-publications.com
study was to evaluate the efficacy of erlotinib, one of the epidermal growth factor receptor-tyrosine
kinase inhibitors (EGFR‑TKIs), in patients … in patients prescribed first‑line erlotinib for …

Randomized, phase III study of gemcitabine or erlotinib maintenance therapy versus observation, with predefined second-line treatment, after cisplatin-gemcitabine …

M Pérol, C Chouaid, D Pérol, F Barlési… - Journal of Clinical …, 2012 - ascopubs.org
… This phase III study investigated whether continuation maintenance with gemcitabine or …
maintenance with erlotinib improves clinical outcome compared with observation in patients with …

[HTML][HTML] Efficacy and safety of erlotinib in elderly patients in the phase IV POLARSTAR surveillance study of Japanese patients with non-small-cell lung cancer

H Yoshioka, K Komuta, F Imamura, S Kudoh, A Seki… - Lung cancer, 2014 - Elsevier
… Efficacy and tolerability of erlotinib for elderly patients was not numerically inferior to that
reported in younger patients. Erlotinib could be considered for elderly patients with recurrent/…

Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian …

IB Vergote, F Joly, D Katsaros, C Coens, A Reinthaller… - 2012 - ascopubs.org
Patients were randomised to maintenance erlotinib 150 mg daily for 2 years or observation.
Primary endpoint was progression-free survival (PFS) by RECIST in combination with GCIG …

Effect of erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 …

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… the erlotinib arm in our studystudy found a longer PFS in the patients with a T790M mutation
detected in pretreatment specimen. This observation has not been validated in other studies