Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation

PA Konstantinopoulos, A Kominea, G Vandoros… - … journal of cancer, 2003 - Elsevier
… expressed in normal and malignant colon, the aim of this … colonic wall and colon cancer.
ERβ expression was evaluated by immunohistochemistry in 90 cases of colon adenocarcinoma

Expression of oestrogen receptor β and prognosis of colorectal cancer

A Rudolph, C Toth, M Hoffmeister, W Roth… - … journal of cancer, 2012 - nature.com
… Previous studies suggest that sex steroids influence colorectal cancer (CRC) carcinogenesis.
The oestrogen receptor β (ERβ) is the predominantly expressed ER in the colon and loss …

[PDF][PDF] Oestrogen-induced apoptosis in colonocytes expressing oestrogen receptor beta

Y Qiu, CE Waters, AE Lewis, MJS Langman… - Journal of …, 2002 - researchgate.net
… In seeking to determine whether, and if so how, E2 protects against colon cancer, we
have assessed the effects of E2 on apoptosis and differentiation in a colon cancer cell line (…

[HTML][HTML] Association of the oestrogen receptor beta with hormone status and prognosis in a cohort of female patients with colorectal cancer

G Topi, R Ehrnström, K Jirström, I Palmquist… - … journal of cancer, 2017 - Elsevier
… Proximal (right-sided) colon cancer is more common among … oestrogen receptor in the
normal colon mucosa, and its loss in CRC has been associated with advanced stages of cancer

Expression of estrogen receptor β in colon cancer progression

F Castiglione, A Taddei… - Diagnostic Molecular …, 2008 - journals.lww.com
colonic tissue. However, the specific effect of estrogens on a normal colon and the role in
the colon … of the estrogen receptors β, β1, β2, and β5 in colon adenocarcinomas and to …

Oestrogen and the colon: potential mechanisms for cancer prevention

R Kennelly, DO Kavanagh, AM Hogan… - The lancet oncology, 2008 - thelancet.com
… (ERβ) and its over expression in healthy human colon coupled with reduced expression in
colon cancer suggests … Selective loss of estrogen receptor beta in malignant human colon. …

Oestrogen receptor-related receptor alpha (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression

A Cavallini, M Notarnicola, R Giannini… - … journal of cancer, 2005 - Elsevier
… the presence of oestrogen receptor-related (ERR) mRNA in human colorectal tumour tissues
… In contrast, oestrogen receptor (ERα and ERβ) mRNA levels were shown to be decreased …

Estrogen receptor β is expressed in human colorectal adenocarcinoma

D Witte, M Chirala, A Younes, Y Li, M Younes - Human pathology, 2001 - Elsevier
… Estrogen receptor β (ER-β) has recently been detected in a human colon cancer cell line. …
whether ER-β is expressed in human colorectal carcinoma (CRC) tissue and the extent of this …

ER-β expression in large bowel adenomas: implications in colon carcinogenesis

A Di Leo, M Barone, E Maiorano, S Tanzi… - Digestive and Liver …, 2008 - Elsevier
… In the present study, we evaluated oestrogen receptor-beta … apoptosis in colorectal adenomas
and normal colon tissue. … in colon adenocarcinoma cells than in normal colon epithelial …

Estrogen receptor beta as target for colorectal cancer prevention

C Williams, A DiLeo, Y Niv, JÅ Gustafsson - Cancer letters, 2016 - Elsevier
… lower incidence of colon adenocarcinoma. Collectively, … of colorectal adenomatous polyps
and prevention of colorectal carcinoma … and clinical evidence of the estrogenic pathway in the …