[HTML][HTML] Old dogs and new tricks

E Ejkova, WP Tansey - EMBO reports, 2002 - embopress.org
… The roles of phosphorylation, acetylation and methylation in gene control are well documented.
It should come as no surprise, therefore, that yet another modification, ubiquitylation, …

Genome-wide DNA methylation analysis using MethylCap-seq in canine high-grade B-cell lymphoma

CH Hsu, H Tomiyasu, JJ Lee, CW Tung… - Journal of Leucocyte …, 2021 - academic.oup.com
DNA methylation analysis of tissues from clinical cases of cHGBL and PBMCs from healthy
dogs … Regarding clinical profile, case 1 is a 10-yr-old female schnauzer with stage IV and …

DNA methylation aging clocks: challenges and recommendations

CG Bell, R Lowe, PD Adams, AA Baccarelli, S Beck… - Genome biology, 2019 - Springer
… challenges that the fascinating discovery of “DNA methylation clocks” has brought into focus.
… a “DNA methylation clock” as an estimator built from epigenetic DNA methylation marks that …

A cost‐effective blood DNA methylation‐based age estimation method in domestic cats, Tsushima leopard cats (Prionailurus bengalensis euptilurus) and Panthera …

H Qi, QL Lim, K Kinoshita, N Nakajima… - Molecular Ecology …, 2024 - Wiley Online Library
… for the age classes 2–6 years old, and most samples over 6 years old came from only two
individuals (… Environmental effects are also associated with DNA methylation change and age …

Quantification of Global DNA Methylation in Canine Mammary Gland Tumors via Immunostaining of 5-Methylcytosine: Histopathological and Clinical Correlations

LR Biondi, MV Tedardi, LB Gentile… - Frontiers in Veterinary …, 2021 - frontiersin.org
dogs, with genetic and epigenetic alterations contributing to canine mammary carcinogenesis.
This study quantified global DNA methylation in 5-… from female dogs were retrospectively …

Age estimation based on blood DNA methylation levels in brown bears

S Nakamura, J Yamazaki, N Matsumoto… - Molecular Ecology …, 2023 - Wiley Online Library
old (Table S_M1 in Appendix S2). Four individuals were rescued in the wild at a few months
old (… Dogs or cats: DNA position or DNA region containing a target corresponding to the CpG …

Age estimation using methylation-sensitive high-resolution melting (MS-HRM) in both healthy felines and those with chronic kidney disease

H Qi, K Kinoshita, T Mori, K Matsumoto, Y Matsui… - Scientific Reports, 2021 - nature.com
… Here, we developed the first DNA methylation-based age-estimation technique—as an …
However, in the CKD male group with both young and old individuals in equal proportions (Fig. 3…

Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci

VJ Sugrue, JA Zoller, P Narayan, AT Lu… - Elife, 2021 - elifesciences.org
… novel factors influencing the aging rate using only DNA methylation data. In this study, we
… Comparable sex-specific methylation differences in MKLN1 also exist in bat skin and a …

[HTML][HTML] A DNA methylation age predictor for zebrafish

B Mayne, D Korbie, L Kenchington, B Ezzy… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
DNA methylation for the use of age estimation. This study highlights the potential further use
of DNA methylation … However, this becomes difficult for fish greater than 10 years old, where …

DNA methylation networks underlying mammalian traits

A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu… - Science, 2023 - science.org
DNA methylation profiles closely parallels that of genetics through evolution. Our results
demonstrate that DNA methylation … The publicly available data from our Mammalian Methylation