Genome-wide DNA methylation profile indicates potential epigenetic regulation of aging in the rhesus macaque thymus

H Qiu, H Li, R Fan, Y Song, X Pan, C Zhang… - International Journal of …, 2022 - mdpi.com
old) and two adult (9 years old) rhesus macaques (Macaca mulatta) to characterize the
genomic DNA methylation … between DNA methylation and gene expression and found that DNA

Epigenetics: it's getting old. Past meets future in paleoepigenetics

D Gokhman, E Meshorer, L Carmel - Trends in ecology & evolution, 2016 - cell.com
… These layers are passed through cellular or organismal generations and include
modifications to the DNA (ie, DNA methylation) and to the proteins that package it (eg, histone …

Genome-wide DNA methylation profile in feline haematological tumours: A preliminary study

J Yamazaki, J Jelinek, S Yokoyama… - Research in veterinary …, 2021 - Elsevier
… Peripheral blood samples were obtained from four healthy volunteer cats (NM1, 4-year-old
female American short hair; NM2, 5-year-old male mixed; NM3 and NM4, 8-month-old male …

Age-Dependent Variations in Functional Quality and Proteomic Characteristics of Canine (Canis lupus familiaris) Epididymal Spermatozoa

A Zmudzinska, J Wisniewski, P Mlynarz… - International Journal of …, 2022 - mdpi.com
… of epididymal spermatozoa of dogs that were differing … dogs that were divided into three
age groups. G1—12 to 41 months old, G2—42 to 77 months old, and G3—78 to 132 months old. …

Early life social and ecological determinants of global DNA methylation in wild spotted hyenas

ZM Laubach, CD Faulk, DC Dolinoy… - Molecular …, 2019 - Wiley Online Library
… a hyena was 3 months old and %CCGG methylation. Our results suggest that … DNA
methylation. Future studies are required to understand the extent to which these DNA methylation

[图书][B] Dog behaviour: Intricate picture of genetics, epigenetics, and human-dog relations

AS Sundman - 2019 - books.google.com
… , of an 8000year-old site identified three differently sized dog types, and remains from …
The aim of this study was to explore DNA methylation in wolf, dog, and different dog species…

The phenotype of aging in the dog: how aging impacts the health and well-being of dogs and their caregivers

BA McKenzie, F Chen… - Journal of the American …, 2022 - Am Vet Med Assoc
… We can often identify an old dog of any breed through a gestalt assessment of appearance,
… age in dogs. Epigenetic changes are modifications to DNA, such as methylation, that …

Dog models of naturally occurring cancer

JL Rowell, DO McCarthy, CE Alvarez - Trends in molecular medicine, 2011 - cell.com
Dogs age five- to eight-fold faster than do humans, share environments with their owners, are
usually kept until old … Moreover, dogs are kept as companion animals well into their old age …

Therapeutic manipulation of ageing: repurposing old dogs and discovering new tricks

V Mallikarjun, J Swift - EBioMedicine, 2016 - thelancet.com
… Cells within old individuals may possess aggregated proteins, dysfunctional mitochondria,
(… More recently, work showing that clearance of senescent cells improves health in old mice ( …

Integrative mapping of the dog epigenome: Reference annotation for comparative intertissue and cross-species studies

KH Son, MBD Aldonza, AR Nam, KH Lee, JW Lee… - Science …, 2023 - science.org
… as histone marks and DNA methylation. To advance the functional annotation of the dog
genome, we … states and methylome-wide profiles across 11 different dog tissues. We defined the …