Intrathecal oligoclonal bands synthesis in multiple sclerosis: is it always a prognostic factor?

J Frau, LM Villar, C Sardu, MA Secci, L Schirru… - Journal of …, 2018 - Springer
… of B cells in the presence of oligoclonal bands (OCB) in the … antibodies correlate with the
intrathecal synthesis of C3 and … are involved in the production of intrathecal IgM. The role of …

The clinical significance of an intrathecal monoclonal immunoglobulin band: a follow-up study

G Davies, G Keir, EJ Thompson, G Giovannoni - Neurology, 2003 - AAN Enterprises
… Other diagnoses compatible with intrathecal oligoclonal band synthesis were also …
Conditions, however, in which intrathecal oligoclonal band synthesis would be unexpected (…

Intrathecal oligoclonal IgG synthesis in multiple sclerosis

A Petzold - Journal of neuroimmunology, 2013 - Elsevier
… Local synthesis: oligoclonal bands are present in the CSF but not in the serum (Type 2).
This pattern is observed in patients with MS. As mentioned above, OCBs are also seen in a …

Intrathecal synthesis of antibodies to human T lymphotropic virus type I and the presence of IgG oligoclonal bands in the cerebrospinal fluid of patients with endemic …

A Gessain, C Caudie, O Gout… - Journal of Infectious …, 1988 - academic.oup.com
synthesis rate and an elevated IgG index, with an increased HTLV-Iantibody-toalbumin ratio
and the presence of CSF oligoclonal bands … CSF IgG oligoclonal bands, IBBB IgG synthesis, …

Intrathecal synthesis of virus-specific oligoclonal antibodies in patients with enterovirus infection of the central nervous system

R Kaiser, R Dörries, R Martin, U Fuhrmeister… - Journal of …, 1989 - Springer
… lated borderline indicating intrathecal synthesis of IgG represents a statistical limit characterized
by a broad biological variance [25], whereas oligoclonal bands are detected individually …

Intrathecal synthesis of oligoclonal IgG in patients with Viliuisk encephalomyelitis: the relationship between oligoclonal bands and clinical features

TM Sivtseva, VA Vladimirtsev, RS Nikitina… - Journal of the …, 2018 - Elsevier
Oligoclonal bands in CSF but not in the serum were found in 34 (58.6%) out of 58 VE patients.
Identical bands … This indicates that the OCBs in these cases are not locally synthesized

Intrathecal synthesis of IgM in neurological diseases: a comparison between detection of oligoclonal bands and quantitative estimation

MK Sharief, G Keir, EJ Thompson - Journal of the neurological sciences, 1990 - Elsevier
… o) showed evidence of intrathecal synthesis of IgM in the form of CSF oligoclonal bands.
Fifty-two patients showed distinctive bands in CSF with no bands in corresponding serum and 2 …

The intrathecal synthesis of virus-specific oligoclonal IgG in multiple sclerosis

CJM Sindic, PH Monteyne, EC Laterre - Journal of neuroimmunology, 1994 - Elsevier
… anti-VZ oligoclonal IgG bands than the CSF as a result of an intrathecal synthesis of IgGs with
… faint but undoubtful anti-VZ oligoclonal bands specific to the CSF (CO(+), lanes at the left). …

Intrathecal synthesis of free immunoglobulin light chains in multiple sclerosis

M Krakauer, HS Nielsen, J Jensen… - Acta neurologica …, 1998 - Wiley Online Library
oligoclonal bands, isolated intrathecal synthesis of lambda FLC was more common than
isolated intrathecal synthesis … we find evidence of intrathecal synthesis of other immunoglobulin …

An Updated Evaluation of Intrathecal IgG Synthesis Markers in Relation to Oligoclonal Bands

F Boufidou, AG Vakrakou, M Anagnostouli, K Patas… - Diagnostics, 2023 - mdpi.com
… We retrospectively applied Auer’s and Reiber’s intrathecal IgG synthesis formulae in a …
puncture and oligoclonal bands (OCBs) detection for demonstrating intrathecal IgG synthesis. A …