The one best test for evaluating the effects of bronchodilator therapy

RW Light, SA Conrad, RB George - Chest, 1977 - Elsevier
… to two drugs, a test must distinguish drug-induced … treatment and from the errors of the
measurement itself. In the present study, the FEV 1 was found to be superior to the other five tests

Acute response to bronchodilator: an imperfect guide for bronchodilator therapy in chronic airflow limitation

GH Guyatt, M Townsend, S Nogradi… - Archives of Internal …, 1988 - jamanetwork.com
… therefore tested the ability of acute change in forced expired volume in one second (FEV
1 ) following inhaled beta agonist to predict long-term symptomatic response to albuterol and …

Bronchodilator reversibility testing in chronic obstructive pulmonary disease

PMA Calverley, PS Burge, S Spencer, JA Anderson… - Thorax, 2003 - thorax.bmj.com
… the ability of bronchodilator testing to differentiate between … or in the selection of patients
for inclusion in treatment trials. … in FEV 1 controlled for the post-bronchodilator FEV 1 value …

[HTML][HTML] A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease

HAM Kerstjens, PLP Brand, MD Hughes… - … England Journal of …, 1992 - Mass Medical Soc
… We tested the hypothesis that long-term treatment directed at both bronchodilation and …
agent), which may in turn be superior to treatment with a single agent (β 2 -agonist alone). …

Bronchodilator responsiveness in patients with COPD

DP Tashkin, B Celli, M Decramer, D Liu… - European …, 2008 - Eur Respiratory Soc
… residual effects of previous bronchodilator therapy) 1, as well as … the best opportunity for
determining optimal bronchodilator … methodologically optimised bronchodilator testing, as in the …

Optimum bronchodilator combinations in chronic obstructive pulmonary disease: what is the current evidence?

MC Miles, JF Donohue, JA Ohar - Drugs, 2012 - Springer
… When evaluating a single bronchodilator, we demand … for combination therapies has not
been specifically tested. … the most optimum combination bronchodilator therapy for our patients, …

Bronchodilator therapy: Comparison of acute response to three methods of administration

EH Chester, I Racz, PB Barlow, GL Baum - Chest, 1972 - Elsevier
… The first day of testing was a control day with hourly testing as noted from 9 AM to 1 PM. …
The tests were then repeated hourly from 9 AM to 1 PM as on the control day. The sequence …

Tests of bronchodilator therapy

CB Payne - Chest, 1978 - journal.chestnet.org
… report entitled "The One Best Test for Evaluating the Effects of Bronchodilator Therapy" by
Light … One cannot say that the persistence of the effects of a drug at 300 minutes represents an …

Alternative methods for assessing bronchodilator reversibility in chronic obstructive pulmonary disease

J Hadcroft, PMA Calverley - Thorax, 2001 - thorax.bmj.com
… groups for future treatment trials. To test this, we have conducted a single blind randomised
… breathing pattern after single and combination bronchodilator treatment, respectively. Mean …

[HTML][HTML] Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease

DP Tashkin, GT Ferguson - Respiratory research, 2013 - Springer
therapy involving two long-acting bronchodilators with … is not sufficiently controlled with
monotherapy (Table 1) [9]. The … The rationale for improved bronchodilation has been tested in …