… vaccine research challenging. Dengvaxia, a dengue vaccine for seropositive individuals
between the ages of 9-45 has been licensed despite the significant challenges. Several other …

… The challenges associated with whole DENV-based vaccine strategies necessitate re-focusing
our attention toward the designed dengue vaccine … If the designed vaccines elicited …

… to dengue vaccine development. The first part of the review presents an overview of dengue
immunity, challenges to vaccine … suitable target epitopes for vaccines is ongoing, and while …

… However, challenges remain in developing a dengue vaccine. This includes considering …
Advances in vaccine technology, ongoing clinical trials, and the search for new platforms …

… have undergone Phase II testing and additional Phase II trials are ongoing ( Table 1 ). … good
animal model continue to make the task of developing a dengue vaccine a challenging one. …

… therapies available turns vaccine development into a socio-economic challenge. In this … A
two-dose regimen, administered 3 months apart, was selected for the ongoing phase 3 efficacy …

… A phase I trial is ongoing for this vaccine strain. Although the chimerization strategy appears
… mice from lethal challenge with dengue 2 virus. J Gen Virol 1988; 69: 2101–2107. 57. …

… Advances and challenges of dengue vaccine development are updated here. … emergence
and re-emergence, several international initiatives are ongoing to bring dengue to worldwide …

… This annual meeting should provide ongoing monitoring and evaluation of dengue vaccine
… better understand the challenges in reporting about dengue vaccines. Strategic training and …

… slowed down the development of Dengue vaccines. Recent advances however have shed
… In this review I outline current concepts and ongoing debates on the above topics. A better …