Long-term safety and efficacy of etrasimod for ulcerative colitis: results from the open-label extension of the OASIS study

S Vermeire, M Chiorean, J Panés… - … Crohn's and Colitis, 2021 - academic.oup.com
… -to-severely active ulcerative colitis [OASIS], etrasimod 2 mg provided significant benefit
versus placebo and was generally well tolerated. This open-label extension [OLE] evaluated …

Infliximab for refractory ulcerative colitis or indeterminate colitis: an openlabel multicentre study

JM Gornet, S Couve, Z Hassani… - Alimentary …, 2003 - Wiley Online Library
… with severe steroid-resistant ulcerative colitis. The placebo-… of severe steroid-resistant active
ulcerative colitis. In the placebo … with steroid-refractory ulcerative colitis; the response rate in …

Safety and efficacy of tofacitinib for treatment of ulcerative colitis: final analysis of OCTAVE Open, an openlabel, long‐term extension study with up to 7.0 years of …

WJ Sandborn, N Lawendy, S Danese… - Alimentary …, 2022 - Wiley Online Library
… Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative
colitis. We present final data from OCTAVE Open, an open-label, long-term extension study. …

An open-label trial of the PPARγ ligand rosiglitazone for active ulcerative colitis

JD Lewis, GR Lichtenstein, RB Stein… - Official journal of the …, 2001 - journals.lww.com
ulcerative colitis. METHODS: Fifteen patients with mild to moderately active ulcerative colitis
despite therapy with 5-aminosalicylic acid compounds were enrolled in an open-label study …

Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial

D Laharie, A Bourreille, J Branche, M Allez, Y Bouhnik… - The Lancet, 2012 - thelancet.com
… , open-label trial compared ciclosporin with infliximab in patients admitted to hospital with
severe colitis. … and had an acute severe flare of ulcerative colitis defined by a Lichtiger score of …

Open-label study of adalimumab in patients with ulcerative colitis including those with prior loss of response or intolerance to infliximab

W Afif, JA Leighton, SB Hanauer… - Inflammatory bowel …, 2009 - academic.oup.com
Background The aim of this study was to assess the clinical benefit and tolerability of
adalimumab, a fully human monoclonal antibody to tumor necrosis factor (TNF), in patients with …

[HTML][HTML] Clinical efficacy and safety of oral Qing-Dai in patients with ulcerative colitis: a single-center open-label prospective study

S Sugimoto, M Naganuma, H Kiyohara, M Arai, K Ono… - Digestion, 1960 - karger.com
… use of oral Qing-Dai in the treatment for ulcerative colitis (UC) patients. Studies exploring …
Methods: The open-label, prospective pilot study was conducted at Keio University Hospital. …

[HTML][HTML] Infliximab versus ciclosporin for steroid-resistant acute severe ulcerative colitis (CONSTRUCT): a mixed methods, open-label, pragmatic randomised trial

JG Williams, MF Alam, L Alrubaiy, I Arnott… - The lancet …, 2016 - thelancet.com
… In this mixed methods, open-label, pragmatic randomised … , unscheduled, with severe
ulcerative colitis and failed to … from the Crohn's and Ulcerative Colitis Questionnaire (CUCQ) …

Long-term efficacy and safety of ozanimod in moderately to severely active ulcerative colitis: results from the open-label extension of the randomized, phase 2 …

WJ Sandborn, BG Feagan, S Hanauer… - … Crohn's and Colitis, 2021 - academic.oup.com
… and efficacy of ozanimod in patients with moderately to severely active ulcerative colitis [UC]
with ≥ 4 years of follow-up in the phase 2 TOUCHSTONE open-label extension [OLE]. …

[HTML][HTML] … to severe ulcerative colitis: results from GO-COLITIS (Golimumab: a Phase 4, UK, open label, single arm study on its utilization and impact in ulcerative Colitis …

CSJ Probert, S Sebastian, DR Gaya… - BMJ Open …, 2018 - bmjopengastro.bmj.com
… Objective GO-COLITIS aimed to measure the effectiveness of subcutaneous golimumab in …
ulcerative colitis (UC) despite conventional treatment. Design GO-COLITIS was an open label