… Neutrophil DNA present in CF sputum can be depolymerized by inhaled rhDNase, resulting
in significant improvements in both lung function and symptoms [64,66]. The introduction of …

… Common challenges in biomarker development for rare lung diseases include limited … both
better lung function response in the sirolimus group and more rapid lung function decline in …

… , lung function and risk of lung cancer, in addition to clinical therapeutic benefits and
patient/market acceptance Citation[9,86–88]. Hence, new biotherapeutics for systemic delivery via …

… with good approximation from measurements of lung mechanics and gas exchange, in …
At the same time, methods for lung function testing have been refined and seem promising …

… lung function tests decades later. We will focus on perinatal factors and outline progress and
opportunities … life factors in lifelong lung trajectory, but important challenges and questions …

… This report details the key gaps and opportunities regarding lung function and structure (Table
1)… A fundamental challenge in pediatric respiratory research is the ability to reliably assess …

… Accordingly, a current major challenge of thoracic RT is to better preserve lung function and
… We will also review the new opportunities and challenges arising from the integration of V/Q …

… widely implement vaccination against SARS-CoV-2 is a challenge. However, within these
challenges also lies opportunities for the continent to leverage this health crisis to improve the …

… to a missed opportunity for early identification of lung cancer. We now know from PLCO data
that, in individuals with a 30+ pack-year smoking history, the hazard ratio for lung cancer in …

… Disappointingly, almost half of the patients in the treatment arm of this study did not tolerate
the trial dosing regimen and exhibited a decline in lung function parameters for unknown …