… studies describe impressive benefits of MSC in renal fibrosis, the safety of stem cell therapy
… in renal fibrosis and propose some potential solutions for future research and development. …

… leading to renal fibrosis, and discusses the challenges and opportunities in developing … us
with unprecedented opportunities for therapeutic interventions of renal fibrosis. In view of the …

… Given the growing evidence for EV-mediated renal diseases, … from stem cells in renal
diseases will be outlined. Finally, we … the challenges of EVs-based therapies for renal diseases. …

… fibrosis are aggravated by genetic renal loss of miRNA-29b in mice, further underpinning the
role of miRNA-29 in fibrosis. … the mouse kidney reduced the fibrosis and inflammation in the …

… , gives an opportunity to stop or reverse kidney fibrosis by … advances in the mechanism
of renal fibrosis and summarize novel … of effective antifibrotic drugs remains challenging. …

… , the cell dynamics coordinating fibrosis, and vessel rarefaction. Finally, we will also
briefly highlight new therapies targeting the renal microvasculature to improve renal function. …

… and progression of renal disease and provide the opportunity to investigate new …
Perhaps the greatest challenge is to understand how to adapt the experimental innovations …

… renal fibrosis. The possible mechanisms, biomarkers, and strategies for prevention and
treatment of renal fibrosis … a comprehensive understanding of the renal fibrosis. Finally, we would …

… therefore increase glomerular pressure and renal ischemia than can in turn induce renal
fibrosis. ETR-A can … One of the main challenges in CKD remains the direct assessment of renal …

… However, up to now no miRNA- or siRNA-based drugs for treatment of renal fibrosis have
been introduced into clinical medicine. This is mostly attributed to challenges encountered …