Challenges and opportunities in drug delivery for wound healing

AJ Whittam, ZN Maan, D Duscher, VW Wong… - Advances in wound …, 2016 - liebertpub.com
… Given the risks for systemic toxicity and less predictable drug delivery to the target tissue,
there has been a significant shift in clinical focus toward localized delivery of drugs for wound …

Challenges and opportunities for drug delivery to the posterior of the eye

FJ Cabrera, DC Wang, K Reddy, G Acharya… - Drug discovery today, 2019 - Elsevier
… in drug delivery as a controlled drug delivery vehicle. Peters and colleagues developed
polyesteramide (PEA) or PLGA microspheres, 10–20 μm in size, as a sustained-delivery system …

Liposomes: opportunities in drug delivery

TM Allen - Drugs, 1997 - Springer
… Liposomal drug delivery systems markedly alter the biodistribution of their associated drugs
by delaying drug clearance, retarding drug metabolism, decreasing the volume of distribution…

Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?

L Sanchez-Covarrubias, LM Slosky… - Current …, 2014 - ingentaconnect.com
… to deliver drugs to the brain. This approach provides a unique opportunity to improve efficacy
of … the BBB for CNS drug delivery, with a particular emphasis on opportunities provided by …

[HTML][HTML] Microbial therapeutics: new opportunities for drug delivery

M Jimenez, R Langer, G Traverso - Journal of Experimental Medicine, 2019 - rupress.org
… Robert Langer from MIT discuss the significant challenges of administering live microorganisms
to patients and the opportunities for drug delivery of these new complex therapeutics. …

Cancer therapeutics-opportunities, challenges and advances in drug delivery

D Kakde, D Jain, V Shrivastava, R Kakde… - Journal of Applied …, 2011 - japsonline.com
… provide opportunities for drug delivery carriers to target cancer. These opportunities include
drug resistance. The innovative approaches of cancer treatment require new concepts of …

Drug delivery to the lungs: Challenges and opportunities

SP Newman - Therapeutic delivery, 2017 - Taylor & Francis
drug delivery is relatively complex because the respiratory tract has evolved defense
mechanisms to keep inhaled drug … barriers, pulmonary drug delivery is adversely affected by the …

Drug delivery to the retina: challenges and opportunities

S Duvvuri, S Majumdar, AK Mitra - Expert opinion on biological …, 2003 - Taylor & Francis
… this review are various strategies currently employed for drug delivery to the posterior
chamber, and novel opportunities that can be exploited to enhance ocular bioavailability of drugs. …

COVID-19: Current developments and further opportunities in drug delivery and therapeutics

S Zafar, MS Arshad, S Fatima, A Ali, A Zaman, E Sayed… - Pharmaceutics, 2020 - mdpi.com
… use, an update on vaccine development and opportunities for vaccine delivery. The World
Health … It is concluded that a suitable candidate delivered through an advanced drug delivery

Drug delivery approaches in addressing clinical pharmacology-related issues: opportunities and challenges

H Wen, H Jung, X Li - The AAPS journal, 2015 - Springer
… using drug delivery systems can also pose serious challenges in developing a drug for the
… there will be great opportunities and challenges in utilizing drug delivery systems to provide …