Dendritic cell-based immunotherapy in multiple myeloma: challenges, opportunities, and future directions

E Verheye, J Bravo Melgar, S Deschoemaeker… - International Journal of …, 2022 - mdpi.com
Immunotherapeutic approaches, including adoptive cell therapy, revolutionized treatment in …
As dendritic cells (DCs) are professional antigen-presenting cells and key initiators of tumor-…

Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy

TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
… Another study identified inflammatory DC in the skin of atopic dermatitis patients and named
these cells inflammatory epidermal dendritic cells (IDECs), which were characterized by the …

Dendritic cells and their role in immunotherapy

A Gardner, Á de Mingo Pulido, B Ruffell - Frontiers in immunology, 2020 - frontiersin.org
… approaches to enhance immunotherapy, in … dendritic cell subsets in regulating the anti-tumor
immune response, as well as the current status of dendritic cell-based immunotherapies, in …

Pathological mobilization and activities of dendritic cells in tumor-bearing hosts: challenges and opportunities for immunotherapy of cancer

AJ Tesone, N Svoronos, MJ Allegrezza… - Frontiers in …, 2013 - frontiersin.org
… of immunosuppressive myeloid cells, which in certain tumors includes dendritic cells (DCs).
DCs are of particular interest in the field of cancer immunotherapy because they induce …

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

A Huber, F Dammeijer, JGJV Aerts… - Frontiers in …, 2018 - frontiersin.org
Dendritic cell (DC) based cancer immunotherapy aims at the activation of the immune system,
and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. …

[HTML][HTML] Dendritic cells based immunotherapy

N Shang, M Figini, J Shangguan, B Wang… - American journal of …, 2017 - ncbi.nlm.nih.gov
… The dendritic cells capture and present antigens, and migrate to draining lymph nodes. In
response to activation via dendritic cell signaling, T cells will elicit anti-tumor responses. …

Dendritic cells in cancer immunotherapy

G Schuler - European journal of immunology, 2010 - Wiley Online Library
… DC initiate and regulate T-cell immunity and are thus the key to optimization of all types of
vaccines. Insights into DC biology offer many opportunities to enhance immunogenicity. In this …

Potential approaches for more successful dendritic cell-based immunotherapy

CLL Chiang, K Balint, G Coukos… - Expert opinion on …, 2015 - Taylor & Francis
… Evidently, DCs offer a unique opportunity for cancer immunotherapy and have been
explored in the clinic with some degree of success. Nevertheless, DC-based immunotherapy

Engineering opportunities in cancer immunotherapy

L Jeanbart, MA Swartz - Proceedings of the National …, 2015 - National Acad Sciences
… Immature or regulatory dendritic cells secrete IL-10 and indoleamine 2,3-… and opportunities
that exist in facilitating and enabling the translation of promising new immunotherapeutic

Dendritic cell–based immunotherapy: state of the art and beyond

KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
… biology of dendritic cells and clinical application of dendritic cell vaccination in cancer,
including strategies currently under investigation to improve the efficacy of dendritic cell vaccines. …