[HTML][HTML] Oral anticoagulant therapy in older adults

J Stuby, M Haschke, T Tritschler, D Aujesky - Thrombosis research, 2024 - Elsevier
oral anticoagulants (DOACs) may be superior in terms of efficacy and safety compared to
vitamin K antagonists in older … OAC guideline recommendations for older adults with AF/VTE. …

Oral anticoagulant therapy for older patients with atrial fibrillation: a review of current evidence

M Bo, E Grisoglio, E Brunetti, Y Falcone… - European Journal of …, 2017 - Elsevier
… Predictably, many older adults have both dementia and AF, but little is known about the
best use of OAT for AF in these individuals along the natural history of dementia. In previous …

Oral anticoagulation in the elderly and frail

RM Bauersachs, J Herold - Hämostaseologie, 2020 - thieme-connect.com
… drug kinetics and toxicity of standard doses of oral anticoagulants (OACs). AF trials showed
… In conclusion, elderly and frail patients requiring anticoagulation for AF or VTE are at higher …

New oral anticoagulants in elderly adults: evidence from a meta‐analysis of randomized trials

P Sardar, S Chatterjee, S Chaudhari… - Journal of the …, 2014 - Wiley Online Library
adults. The suggested predisposing factors are low body mass index in frail and the oldest-old
adults, … in older individuals.15-17 No randomi-zed trial has specifically randomized elderly …

Trends in use of oral anticoagulants in older adults with newly diagnosed atrial fibrillation, 2010-2020

D Ko, KJ Lin, LG Bessette, SB Lee, AJ Walkey… - JAMA Network …, 2022 - jamanetwork.com
… Importance Undertreatment of older adults with atrial fibrillation with anticoagulation … direct
oral anticoagulants (DOACs) would improve oral anticoagulant (OAC) initiation in older adults

Use of oral anticoagulant therapy in older adults with atrial fibrillation after acute ischemic stroke

ER McGrath, AS Go, Y Chang… - Journal of the …, 2017 - Wiley Online Library
… to anticoagulation in older adults with atrial fibrillation (AF) at high risk of stroke and to
identify opportunities for interventions that might increase use of oral anticoagulants (OACs). …

Net clinical benefit of oral anticoagulation among older adults with atrial fibrillation

SJ Shah, DE Singer, MC Fang, K Reynolds… - … Quality and Outcomes, 2019 - Am Heart Assoc
anticoagulants in these older adults. To examine the net clinical benefit of anticoagulation in
older adults… study using a cohort of nearly 15 000 adults 75 years and older with incident AF. …

Effect of new oral anticoagulants on prescribing practices for atrial fibrillation in older adults

RB Fohtung, E Novak, MW Rich - Journal of the American …, 2017 - Wiley Online Library
older adults. The purpose of this study was therefore to examine changes in anticoagulation
prescribing practices for older adults … status with use of anticoagulation and trends in uptake …

Direct oral anticoagulants in frail older adults: a geriatric perspective

P Ho, B La Brooy, L Hayes… - Seminars in thrombosis …, 2015 - thieme-connect.com
older population, particularly in the frail older adults where the greatest concern remains. …
Moreover, in all older adults patients where a DOAC is being used, we suggest regular 3 to 6 …

Frailty and clinical outcomes of direct oral anticoagulants versus warfarin in older adults with atrial fibrillation: a cohort study

DH Kim, A Pawar, JJ Gagne, LG Bessette… - Annals of internal …, 2021 - acpjournals.org
… The role of frailty in the choice between a direct oral anticoagulant (DOAC) and warfarin is
… The role of differing levels of frailty in the choice of oral anticoagulants for older adults with …