Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature

F Dentali, N Riva, M Crowther, AGG Turpie, GYH Lip… - Circulation, 2012 - Am Heart Assoc
… the novel oral anticoagulants with the vitamin K antagonists in patients with atrial fibrillation.
We … We found that the novel oral anticoagulants significantly reduced overall mortality, …

Influence of direct oral anticoagulants on rates of oral anticoagulation for atrial fibrillation

LN Marzec, J Wang, ND Shah, PS Chan… - Journal of the American …, 2017 - jacc.org
Oral anticoagulation (OAC) is recommended to reduce the risk of stroke associated with
nonvalvular atrial fibrillation … Warfarin is the most widely prescribed oral anticoagulant in the …

New oral anticoagulants in atrial fibrillation

AGG Turpie - European heart journal, 2008 - academic.oup.com
Atrial fibrillation (AF) is a major risk factor for stroke. Currently, acetylsalicylic acid (a platelet
inhibitor) and vitamin K antagonists (VKAs; oral anticoagulants), including warfarin, are the …

Underuse of oral anticoagulants in atrial fibrillation: a systematic review

IM Ogilvie, N Newton, SA Welner, W Cowell… - The American journal of …, 2010 - Elsevier
… of oral anticoagulation therapy for real-world atrial fibrillation patients with an elevated risk
of stroke, highlighting the need for improved therapies for stroke prevention in atrial fibrillation. …

Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis

C van Walraven, RG Hart, DE Singer, A Laupacis… - Jama, 2002 - jamanetwork.com
… of oral anticoagulants vs aspirin (with or without low-dose warfarin) is presented for all 6
outcomes as a hazard ratio. Hazard ratios below 1 indicate that oral anticoagulant decreases …

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

CT Ruff, RP Giugliano, E Braunwald, EB Hoffman… - The Lancet, 2014 - thelancet.com
… This meta-analysis is the first to include data for all four new oral anticoagulants studied in …
embolic events in patients with atrial fibrillation. New oral anticoagulants had a favourable risk…

Novel oral anticoagulants in atrial fibrillation: a meta‐analysis of large, randomized, controlled trials vs warfarin

A Dogliotti, E Paolasso, RP Giugliano - Clinical Cardiology, 2013 - Wiley Online Library
… In this meta-analysis of the 5 large phase III trials of novel oral anticoagulants compared
to warfarin in patients with atrial fibrillation, statistically significant reductions in the primary …

Oral anticoagulants for stroke prevention in atrial fibrillation: current status, special situations, and unmet needs

FWA Verheugt, CB Granger - The Lancet, 2015 - thelancet.com
… In patients with non-valvular atrial fibrillation, oral anticoagulation with vitamin K antagonists
reduces the risk of stroke by more than 60%. But vitamin K antagonists have limitations, …

Oral anticoagulation use by patients with atrial fibrillation in Germany

T Wilke, A Groth, S Mueller… - Thrombosis and …, 2012 - thieme-connect.com
Atrial fibrillation (AF) is the most common significant cardiac rhythm disorder. Oral
anticoagulation (OAC) is recommended by guidelines in the presence of a moderate to high risk of …

Comparative efficacy and safety of new oral anticoagulants in patients with atrial fibrillation

S Schneeweiss, JJ Gagne, AR Patrick… - … Quality and Outcomes, 2012 - Am Heart Assoc
… , an oral thrombin inhibitor, and rivaroxaban and apixaban, oral factor Xa inhibitors, have
been found to be safe and effective in reducing stroke risk in patients with atrial fibrillation. We …