Direct oral anticoagulants: efficacy and safety in patient subgroups

TA Mavrakanas, C Samer, P Fontana, A Perrier - Swiss medical weekly, 2015 - smw.ch
oral anticoagulants have recently emerged as an attractive choice for patients requiring
anticoagulation … doses without the need for routine anticoagulation monitoring. They may present …

Efficacy and safety considerations with dose-reduced direct oral anticoagulants: a review

B Bikdeli, FZ Tajrishi, P Sadeghipour… - JAMA …, 2022 - jamanetwork.com
… Dose-reduced regimens of direct oral anticoagulants (DOACs) may be used for 2 main
purposes: dose-adjusted treatment intended as full-intensity anticoagulation (eg, for stroke …

The efficacy and safety of direct oral anticoagulants vs traditional anticoagulants in cirrhosis

J Hum, JJ Shatzel, JH Jou… - European journal of …, 2017 - Wiley Online Library
oral anticoagulant use in patients with cirrhosis may be as safe as traditional anticoagulants.
… less major bleeding events, while maintaining efficacy at preventing stroke or thrombosis. …

A review of the efficacy and safety profiles of the novel oral anticoagulants in the treatment and prevention of venous thromboembolism

AA Coulis, WC Mackey - Clinical therapeutics, 2018 - Elsevier
… This study aims to review the published literature concerning the use of novel oral
anticoagulants (NOACs) in the treatment and prevention of venous thromboembolism (VTE) and to …

Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature

F Dentali, N Riva, M Crowther, AGG Turpie, GYH Lip… - Circulation, 2012 - Am Heart Assoc
… We found that the novel oral anticoagulants significantly … The novel oral anticoagulants may
potentially address some … and a more predictable anticoagulant effect, thus allowing fixed-…

Efficacy and safety of novel oral anticoagulants in clinical practice: a report from three centers in Sweden

A Labaf, M Carlwe, PJ Svensson - Thrombosis journal, 2014 - Springer
… In clinical trials new oral anticoagulants (NOAC) have proved … The aim of this study was to
evaluate the efficacy and safety … was to evaluate the efficacy and safety of treatment with NOAC …

Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis

RCP Makam, DC Hoaglin, DD McManus, V Wang… - PloS one, 2018 - journals.plos.org
Background Direct oral anticoagulants (DOACs) have emerged as promising alternatives to
vitamin K antagonists (VKAs) for patients with non-valvular atrial fibrillation (NVAF) or …

Real-world safety and efficacy of direct oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of 605 771 patients

D Menichelli, F Del Sole, A Di Rocco… - European Heart …, 2021 - academic.oup.com
… To analyse the safety and efficacy of direct oral anticoagulants (DOACs) in real-world …
Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation …

Safety of new oral anticoagulants

MSV Sarrazin, A Rose - BMJ, 2015 - bmj.com
… among patients taking the novel oral anticoagulants dabigatran and rivaroxaban.1 … oral
anticoagulants for atrial fibrillation are typically older than those receiving anticoagulation for …

Direct oral anticoagulants: evidence and unresolved issues

N Chan, M Sobieraj-Teague, JW Eikelboom - The Lancet, 2020 - thelancet.com
… Direct oral anticoagulants are contraindicated in patients with … the pharmacology of direct
oral anticoagulants, summarise the … perspectives for the development of oral anticoagulants. …