… As with all anticoagulants, treatment with DOACs is associated with a risk of major bleeding,
including life-threatening gastrointestinal bleeds and intracranial hemorrhages (ICHs). In …

… and based on the published major developments in oral anticoagulant reversal since the …
deal with oral anticoagulant reversal in major hemorrhage and the need for urgent surgery. …

… Second, this meta-analysis identified important differences in major bleeding events with
newer oral anticoagulants in different indications. Differences also exist with the type of surgical …

… patients who experienced major bleeding during anticoagulant therapy. In total, 1,121 major
bleeds occurred in 1,034 patients with no significant difference in annualized bleeding rates …

… of anticoagulant treatment. This review reports data on the rates of major bleeding with old
and new oral anticoagulants… of anticoagulation in patients treated with oral anticoagulants and …

… patients aged more than 18 years presenting with major bleeding or thromboembolic
complications. In this article, we only report data on patients presenting with major bleeding events. …

… for bleeding on anticoagulants The use of VKA is associated with an annual increase in
major bleeding … Several determinants of major bleeding during treatment with VKA have been …

… across the 3 types of major bleeding, and we therefore … that bleeding risk related to oral
anticoagulants was mostly related to patient characteristics, not to the indication for anticoagulant …

… anticoagulant treatment. During treatment with vitamin K … of major bleeding (MB) and
fatal bleeding is estimated to be 2–5% and 0.5–1% per year [1], [2]. Direct oral anticoagulants (…

… Rates of major bleeding among patients receiving NOACs are comparable to or lower than
… of major bleeding among studies likely relates to differences in definition of major bleeding, …