Characterization of a reproducible gastric pain model using oral capsaicin titration in healthy volunteers

Y Cao, CH Wilder‐Smith, XH Li… - …, 2011 - Wiley Online Library
… (19), whereas in our study almost half of the healthy subjects reached stable moderate pain
using exactly the same dose. Possible reasons for this discrepancy may be differences in …

A placebo‐controlled trial of an oral capsaicin load in patients with functional dyspepsia

M Führer, H Vogelsang… - Neurogastroenterology & …, 2011 - Wiley Online Library
Subjects were randomized to receive either a capsaicin or a placebo capsule in a double-blind
fashion. None of the healthy subjects had a history of GI disease or abdominal surgery …

Capsaicin as new orally applicable gastroprotective and therapeutic drug alone or in combination with nonsteroidal anti-inflammatory drugs in healthy human subjects …

G Mózsik - Capsaicin as a Therapeutic Molecule, 2014 - Springer
… The healthy subjects received intragastrically capsaicin (100, 200, 400 and 800 μg ig.), …
–50 mg, famotidine (20–40 mg orally), ranitidine (150–300 mg orally), cimetidine (100–1000 mg …

Somatosensory profiling of intra‐oral capsaicin and menthol in healthy subjects

S Lu, L Baad‐Hansen, T List, Z Zhang… - … journal of oral …, 2013 - Wiley Online Library
… of capsaicin to induce intra-oral experimental pain. The desensitization effects of capsaicin
to explain the desensitization effect caused by capsaicin. One prevailing hypothesis is that an …

Capsaicin and glucose absorption and utilization in healthy human subjects

A Dömötör, J Szolcsányi, G Mózsik - European journal of pharmacology, 2006 - Elsevier
… to 180 min after capsaicin administration in human healthy subjects given 75 g glucose orally.
The … ; however, levels did not differ significantly without or with capsaicin (400 μg orally). …

[HTML][HTML] Gastroprotection induced by capsaicin in healthy human subjects

G Mózsik, J Szolcsányi, I Rácz - World Journal of Gastroenterology …, 2005 - ncbi.nlm.nih.gov
… , pure capsaicin solution was injected into the stomach (1-8 μg/mL in 100 mL) of healthy
subjects … On the human oral mucosa, this concentration of capsaicin induces some diminished …

[HTML][HTML] Effects of oral stimulation with capsaicin on salivary secretion and neural activities in the autonomic system and the brain

Y Kono, A Kubota, M Taira, N Katsuyama… - Journal of Dental …, 2018 - Elsevier
oral stimulation with capsaicin has not been elucidated. Therefore, we investigated the effect
of oral capsaicin stimulation on oral health … among subjects except for capsaicin, which was …

[HTML][HTML] Possible effects of capsaicin (Chili pepper) on the Oral Health

R Menicagli, O Marotta, N Maione - International Journal of …, 2020 - journals.lww.com
… In our study, the contact of capsaicin to oral mucosa causes a similar inflammatory process,
… When we apply the capsaicin to the oral mucosa, it induces a nociceptive effect of the oral

Detection and modulation of capsaicin perception in the human oral cavity

G Smutzer, JC Jacob, JT Tran, DI Shah, S Gambhir… - Physiology & …, 2018 - Elsevier
… perception in the absence of nasal airflow, subjects were tested for oral capsaicin intensity
where airflow through the nose was fully blocked by a plastic clamp (Phipps and Bird, …

The effects of capsaicin-induced intraoral mucosal pain on jaw movements in humans.

NN Zhao, T Whittle, GM Murray… - Journal of orofacial …, 2012 - search.ebscohost.com
capsaicin, the pungent … capsaicin applied to the oral mucosa is an appropriate model of
clinical mucosal pain. When applied topically to the oral mucosa in healthy subjects, capsaicin