… of microenvironmental pH and release of pH-modifier would … appropriate pH-modifier and
optimization of the formulation. … excipients as a pH-modifier in the formulation, leading to pH-…

… In general, weakly basic drugs sometimes exhibit poor oral bioavailability with wide …
low oral bioavailability in famotidine-treated patients with increased gastric pH, and the oral …

… This analysis provides an improved formulation design procedure using pH modifiers by
minimizing the experimental iterations under both in vitro and in vivo conditions. …

… performance of oral formulations of dipyridamole, which contained fumaric acid as a pH
modifier. … from various formulations, the D/P system is a useful tool to design and select better …

… The present study was undertaken to develop a granule formulation of DP (DPG) with an
acidic pH-modifier for improving dissolution properties and oral bioavailability of DP with low …

… formulations (F1, F2, and F3) showed improvement in drug release as compared to the
formulation without pH modifier (F0… of acidifiers in modified release oral formulation of cinnarizine. …

… KZ using organic acids as pH-modifiers. The purpose of this study is to (A) develop a solid
oral formulation containing KZ as a model compound and organic acids as pH-modifiers, (B) …

… The purpose of this study is to clarify the process of dissolution and precipitation of telmisartan
in the gastrointestinal tract from its oral formulation containing meglumine, a pH modifier (…

… of pH modifiers should be added in the formulations, and the appropriate methods of … of
pH M modification in the oral cavity is discussed. The drug candidates, pH modifiers and pH M …

… Dissolution-modulating mechanism of pH modifiers in solid dispersion containing weakly …
Formulation development of oral controlled release tablets of hydralazine: Optimization of …