Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence

A Gillenwater, R Jacob, R Ganeshappa… - … –head & neck …, 1998 - jamanetwork.com
… The results of this study demonstrate the ability of fluorescence spectroscopy to differentiate
between neoplastic and nonneoplastic oral cavity tissue in vivo. Comparisons of neoplastic

Objective detection and delineation of oral neoplasia using autofluorescence imaging

D Roblyer, C Kurachi, V Stepanek, MD Williams… - Cancer prevention …, 2009 - AACR
… We present a new method to objectively delineate neoplastic oral mucosa using autofluorescence
imaging. Autofluorescence images were obtained from 56 patients with oral lesions …

Understanding the biological basis of autofluorescence imaging for oral cancer detection: high-resolution fluorescence microscopy in viable tissue

I Pavlova, M Williams, A El-Naggar… - Clinical Cancer …, 2008 - AACR
autofluorescence properties of oral tissue. Third, we compared the autofluorescence patterns
of oral cancers … alteration in autofluorescence in epithelial and stromal layers during oral

The status of in vivo autofluorescence spectroscopy and imaging for oral oncology

DCG De Veld, MJH Witjes, H Sterenborg… - Oral oncology, 2005 - Elsevier
… of autofluorescence imaging for the detection of oral cancer, … vivo autofluorescence in normal
and malignant oral tissues. … normal and 15 malignant oral tissue samples from 15 oncology …

Vision enhancement system for detection of oral cavity neoplasia based on autofluorescence

E Svistun, R Alizadeh‐Naderi… - Head & Neck …, 2004 - Wiley Online Library
… The conventional clinical method of oral cancer diagnosis relies on evaluation of tissue
tissue autofluorescence, in which optical contrast between normal and neoplastic tissue

Autofluorescence characteristics of oral mucosa

DR Ingrams, JK Dhingra, K Roy, DF Perrault Jr… - Head & …, 1997 - Wiley Online Library
tissues.Autofluorescence from malignant tumor was observed by Policard as early as 1924…
Alfano et al8 in 1984 conclusively showed that autofluorescence can effectively differentiate …

Autofluorescence imaging and spectroscopy of normal and malignant mucosa in patients with head and neck cancer

CS Betz, M Mehlmann, K Rick, H Stepp… - Lasers in Surgery …, 1999 - Wiley Online Library
… This investigation aims to evaluate the value of autofluorescence photodetection of oral
neoplasms in the green spectral range utilizing a band of excitation wavelengths in the near UV …

Assessment of tissue autofluorescence and reflectance for oral cavity cancer screening

L Sweeny, NR Dean, JS Magnuson… - … --Head and Neck …, 2011 - journals.sagepub.com
… with autofluorescence that were not already apparent on white light examination. Similarly,
we found that use of tissue autofluorescence in previously treated head and neck cancer

Efficacy of tissue autofluorescence imaging (VELScope) in the visualization of oral mucosal lesions

CS Farah, L McIntosh, A Georgiou… - Head & neck, 2012 - Wiley Online Library
… Patients known to have oral epithelial dysplasia or squamous cell carcinoma were not
included in this study. The study was conducted according to Human Ethics Guidelines approved …

Autofluorescence imaging in recurrent oral squamous cell carcinoma

M Scheer, J Fuss, MA Derman, M Kreppel… - Oral and maxillofacial …, 2016 - Springer
… health care professionals the ability to estimate persistent oral lesions of uncertain biological
significance early. Especially tissue autofluorescence imagining has much interest. The …