Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study

A Blet, B Deniau, K Santos, DPT van Lier, F Azibani… - Critical care, 2021 - Springer
Background Dipeptidyl peptidase 3 (DPP3) is a cytosolic enzyme involved in the degradation
of various cardiovascular and endorphin mediators. High levels of circulating DPP3 (…

Dipeptidyl peptidase II (DPPII), a review

MB Maes, S Scharpé, I De Meester - Clinica chimica acta, 2007 - Elsevier
An increasing number of biological processes appear to be regulated by Pro-specific N-terminal
processing. The proline-specific dipeptidyl peptidases (DPPs) like DPPIV, fibroblast …

… mortality and organ failure after open and endovascular thoraco-abdominal aortic surgery can be predicted by increased levels of circulating dipeptidyl peptidase 3

A Gombert, M Barbati, D Kotelis… - European journal of …, 2021 - academic.oup.com
dipeptidyl peptidase 3 (cDPP3) is a novel biomarker that shows a strong association with
organ failure … patient survival and organ failure following open and endovascular TAAA repair. …

High plasma dipeptidyl peptidase 3 levels are associated with mortality and organ failure in shock: results from the international, prospective and observational FROG …

B Deniau, A Picod, D Van Lier, PV Ayar… - British Journal of …, 2022 - bjanaesthesia.org
… Circulating dipeptidyl peptidase 3 (cDPP3) is a metallo-peptidase involved in the … The link
between cDPP3 levels and the occurrence of shock and organ failure is not clear. Clinical and …

Promotion of vascular integrity in sepsis through modulation of bioactive adrenomedullin and dipeptidyl peptidase 3

D Van Lier, M Kox, P Pickkers - Journal of Internal Medicine, 2021 - Wiley Online Library
… of organ dysfunction and mortality. In this review, we focus on dipeptidyl peptidase 3 (DPP3) …
All these factors ultimately contribute to the development of organ failure, which is the key …

Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients

F Dépret, J Amzallag, A Pollina, L Fayolle-Pivot… - Critical care, 2020 - Springer
… While the prognosis of burn patients has improved, the mortality of most severe patients
remains high with many patients dying from circulatory failure and multiple organ failure [16, 17]. …

Targeting cluster of differentiation 26/dipeptidyl peptidase 4 (CD26/DPP4) in organ fibrosis

B Ohm, I Moneke… - British Journal of …, 2023 - Wiley Online Library
… chronic diseases eventually resulting in fatal organ failure. Due to the excruciating disease
… and the associated rates of organ failure in multiple disease entities of chronic organ injury. …

Circulating dipeptidyl peptidase 3 on intensive care unit admission is a predictor of organ dysfunction and mortality

A Frigyesi, M Lengquist, M Spångfors, M Annborn… - Journal of Intensive …, 2021 - Springer
… potential of circulating dipeptidyl peptidase 3 (cDPP3) to predict mortality and development
of organ … The association of cDPP3 levels with 30-day mortality and Sequential Organ Failure

The contributions of dipeptidyl peptidase IV to inflammation in heart failure

T de Almeida Salles, C Zogbi… - American Journal …, 2016 - journals.physiology.org
dipeptidyl peptidase IV (DPPIV) inhibition improves cardiac perfusion and inflammation in an
experimental model of heart failure (… dipeptidyl peptidase IV (DPPIV), also known as CD26, …

Potential role of dipeptidyl peptidase IV in the pathophysiology of heart failure

TA Salles, L Dos Santos, VG Barauna… - International Journal of …, 2015 - mdpi.com
Dipeptidyl peptidase IV (DPPIV) is a widely expressed multifunctional serine peptidase that
exists as a membrane-anchored cell surface protein or in a soluble form in the plasma and …