Mechanisms and pathogenesis underlying environmental chemical-induced necroptosis

MR Sepand, M Aliomrani, Y Hasani-Nourian… - … Science and Pollution …, 2020 - Springer
… , and it seems that necroptosis inhibition can reduce the side effects of chemicals. Here we
introduce mechanism and pathogenesis of necroptosis as an emerging molecular pathway, …

The role of necroptosis in disease and treatment

X Liu, X Xie, Y Ren, Z Shao, N Zhang, L Li, X Ding… - MedComm, 2021 - Wiley Online Library
… can reduce inflammation and contribute to reducing damage and protecting organs. In alcoholic
… Taken together, how necroptosis contributes to liver injury pathogenesis remains to be …

[HTML][HTML] Regulated necrosis in kidney ischemia-reperfusion injury

A Pefanis, FL Ierino, JM Murphy, PJ Cowan - Kidney international, 2019 - Elsevier
… loss, and organ failure. It has been proposed that the participation of necroptosis in certain
… These results indicate a role for ferroptosis in the pathogenesis of renal IRI in this model, …

The role of neutrophil NETosis in organ injury: novel inflammatory cell death mechanisms

Z Cahilog, H Zhao, L Wu, A Alam, S Eguchi, H Weng… - Inflammation, 2020 - Springer
… Cell death is commonly segregated into necrosis and apoptosis… to tissue injury and exacerbate
the extent of organ damage, … its underlying pathogenesis for therapeutic interventions. …

Necroptosis, in vivo detection in experimental disease models

S Jouan-Lanhouet, F Riquet, L Duprez… - Seminars in cell & …, 2014 - Elsevier
… uniquely associated with induction of necroptosis, however recent evidence … necroptosis
identification and discuss past and recent data to provide an update of the so-called “necroptosis

Necroptosis: a potential, promising target and switch in acute pancreatitis

G Wang, FZ Qu, L Li, JC Lv, B Sun - Apoptosis, 2016 - Springer
… of necroptosis in AP to provide a reference for deeply understanding the pathogenic
cytokine network, thereby causing SIRS and multiple organs injuries outside the pancreas [6]. On …

Apoptosis and necroptosis in the liver: a matter of life and death

RF Schwabe, T Luedde - Nature reviews Gastroenterology & …, 2018 - nature.com
… of apoptosis and necroptosis in acute liver injury, nonalcoholic … –reperfusion injury is another
form of acute organ injury and has … is a fundamental element in the disease pathogenesis. …

Molecular mechanisms of liver injury: apoptosis or necrosis

K Wang - Experimental and Toxicologic Pathology, 2014 - Elsevier
… of the liver injury. This review summarizes the characteristics of both hepatic apoptosis
and necrosis in pathogenesis of liver diseases. Apoptosis and necrosis represent alternative …

Circulating Markers of Necroptosis in Acute Pancreatitis

H Belfrage, K Kuuliala, A Kuuliala, H Mustonen… - Digestive Diseases and …, 2024 - Springer
… (SAP) with substantial necrosis of acinar cells, leading to … and potentially systemic inflammation
and organ failure (OF) with … that necroptosis plays a significant role in the pathogenesis of …

The double-edged functions of necroptosis

K Ye, Z Chen, Y Xu - Cell Death & Disease, 2023 - nature.com
… implicated in the pathogenesis of many diseases, there is evidence to support that necroptosis
is not … Necroptosis can result in circulatory failure, organ injury, and lethality [19]. Table 1 …