Autophagy and necroptosis in cisplatin-induced acute kidney injury: Recent advances regarding their role and therapeutic potential

N Alassaf, H Attia - Frontiers in Pharmacology, 2023 - frontiersin.org
pathogenesis of CP-induced renal injury. … necroptosis and inflammation in this auto-amplification
loop could further promote kidney damage, leading to fibrosis and chronic organ failure. …

The molecular pathogenesis of endotoxic shock and organ failure

R Karima, S Matsumoto, H Higashi… - Molecular medicine today, 1999 - cell.com
… sequential multiple organ failure have … failure, leukocyte-induced tissue injury and coagulation
disorder appear to be critical determinants in the development of sequential organ failure. …

Necroptosis triggers spatially restricted neutrophil-mediated vascular damage during lung ischemia reperfusion injury

W Li, Y Terada, YY Tyurina, VA Tyurin… - Proceedings of the …, 2022 - National Acad Sciences
… We discovered that necroptotic death of graft cells regulates … pathogenic mechanisms of lung
ischemia reperfusion injury, … trigger inflammatory responses after organ transplantation (21, …

Necroptosis in pulmonary diseases: a new therapeutic target

L Wang, L Zhou, Y Zhou, L Liu, W Jiang… - Frontiers in …, 2021 - frontiersin.org
… through the release of damage-associated molecular patterns … suggests that necroptosis is
implicated in the pathogenesis of … of necroptosis and its contribution toward the pathogenesis

Activation of necroptosis pathway in podocyte contributes to the pathogenesis of focal segmental glomerular sclerosis

H Hu, M Li, B Chen, C Guo, N Yang - Clinical and Experimental …, 2022 - Springer
injury mouse model, while necroptosis inhibition reduced organ damage and renal failure
[19]… There are also studies that demonstrate the importance of necroptosis in podocyte injury

Histones and neutrophil extracellular traps enhance tubular necrosis and remote organ injury in ischemic AKI

D Nakazawa, SV Kumar, J Marschner… - Journal of the …, 2017 - journals.lww.com
… that may cause remote organ damage. In hypoxia-induced tubular epithelial cell necrosis in
vitro, … mice would be useful for understanding the pathogenesis between necrosis and NETs. …

[HTML][HTML] Programmed cell death in diabetic nephropathy: a review of apoptosis, autophagy, and necroptosis

NS Erekat - Medical Science Monitor: International Medical Journal …, 2022 - ncbi.nlm.nih.gov
… Chronic hyperglycemia results in the dysfunction and failure of different organs, … Necroptosis
is involved in the pathogenesis of diabetic nephropathy [136]. Podocyte necroptosis has …

Necrostatin-1 accelerates time to death in a rat model of cecal ligation and puncture and massively increases hepatocyte caspase-3 cleavage

Q Zhang, S Wei, J Lu, W Fu, H Chen… - American Journal …, 2019 - journals.physiology.org
… inhibited inflammation in multiple organs and protected mice … that necroptosis plays a
protective role in the pathogenesis of … caused by necroptosis, and second, necroptosis blocked …

The role of extracellular histone in organ injury

E Silk, H Zhao, H Weng, D Ma - Cell death & disease, 2017 - nature.com
… , which occurs extensively in pathologies precipitating acute organ injury. ‘Necrosis’ results
… There now exists a vast body of literature that demonstrates histone-mediated pathogenesis

The role of necroptosis in common respiratory diseases in children

J Ning, L Qiao - Frontiers in Pediatrics, 2022 - frontiersin.org
… in the development of lung injury and is involved in the pathogenesis of a variety of lung …
parenchymal I/R injury is similar to that of reperfusion injury in other organs, a process that …