Deer antler–a novel model for studying organ regeneration in mammals

C Li, H Zhao, Z Liu, C McMahon - … journal of biochemistry & cell biology, 2014 - Elsevier
… probably offer the most pertinent model for studying organ regeneration in mammals. This
regeneration of antlers, and provides insights into the possible use for human regenerative

Deer antlers: a zoological curiosity or the key to understanding organ regeneration in mammals?

JS Price, S Allen, C Faucheux, T Althnaian… - Journal of …, 2005 - Wiley Online Library
… mammalian organ regeneration. No other mammal can naturally regenerate any lost organ,
… and complex as an antler, eg the antlers of a 200-kg adult red deer may weigh as much 30 …

Adult stem cells and mammalian epimorphic regeneration-insights from studying annual renewal of deer antlers

C Li, F Yang, A Sheppard - Current stem cell research & …, 2009 - ingentaconnect.com
organ replacement is known as epimorphic regeneration. To … Antler stem cells reside in the
pedicle periosteum. We … regeneration of mammalian appendages, other than antler, could be …

[HTML][HTML] Deer antler stem cells are a novel type of cells that sustain full regeneration of a mammalian organdeer antler

D Wang, D Berg, H Ba, H Sun, Z Wang, C Li - Cell Death & Disease, 2019 - nature.com
… of the AS cells in the present study would help our understanding of the mechanism
underlying antler regeneration, the only stem cell-based full organ regeneration in mammals. …

Proteomic profiling of stem cell tissues during regeneration of deer antler: A model of mammalian organ regeneration

Z Dong, S Haines, D Coates - Journal of proteome research, 2020 - ACS Publications
… As the only known mammalian organ that can fully and annually regenerate, deer antler
has … of stem-cell-based organ regeneration. Antler regeneration is known to be initiated and …

Deer antler regeneration: a stem cell‐based epimorphic process

C Li - Birth Defects Research Part C: Embryo Today: Reviews, 2012 - Wiley Online Library
… Full regeneration of deer antlers, a bona fide epimorphic process in mammals, is in … a better
position to promote organ regeneration in humans. Antler regeneration takes place in yearly …

[HTML][HTML] New physiological insights into the phenomena of deer antler: A unique model for skeletal tissue regeneration

M Feleke, S Bennett, J Chen, X Hu, D Williams… - Journal of Orthopaedic …, 2021 - Elsevier
organ regeneration process in mammals, the deer antler represents a prime model system for
investigating mechanisms of regeneration … -based therapies for regenerative medicine and …

Evidence that the canonical Wnt signalling pathway regulates deer antler regeneration

JG Mount, M Muzylak, S Allen… - … dynamics: an official …, 2006 - Wiley Online Library
… is evidence for its recapitulation during organ regeneration in lower vertebrates. This … deer
antlers, frontal bone appendages that are the only mammalian organs capable of regeneration

Deer antlers as a model of mammalian regeneration

J Price, C Faucheux, S Allen - Current topics in developmental biology, 2005 - Elsevier
… the ability to regenerate organs. … regenerating antlers. This apparent lack of any specific
‘antlerogenic molecular machinery’ suggests that the secret of deers’ ability to regenerate antlers

[HTML][HTML] Deer antler renewal gives insights into mammalian epimorphic regeneration

C Li - Cell Regeneration, 2023 - Springer
Deer antlers are the only known mammalian organ that, … of the old antler and regeneration
of the new antler are not … follow one another in most deer species. This conclusion was also …