Serum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer

J He, Z Han, W Luo, J Shen, F Xie, L Liao… - Frontiers in …, 2023 - frontiersin.org
… (d) Diagnostic model of serum organic acid metabolites for … of organic acid metabolites in
the serum of prostate canceracid, citric acid, malic acid, and phenyllactic acid in the serum …

A study of low-molecular-weight organic acid urinary profiles in prostate cancer by a new liquid chromatography-tandem mass spectrometry method

A Klupczynska, S Plewa, N Sytek, W Sawicki… - … of Pharmaceutical and …, 2018 - Elsevier
cancer patients: ≥7 Gleason patients and <7 Gleason patients. Quick sample … acids
metabolism. The research also broadens our knowledge on the alteration of selected organic acids

Identification of the metabolic signatures of prostate cancer by mass spectrometry‐based plasma and urine metabolomics analysis

C Yu, L Niu, L Li, T Li, L Duan, Z He, Y Zhao… - … Prostate, 2021 - Wiley Online Library
Organic acids in dried urine spots were quantified by using GC-MS (Supplemental files:
Table S1). Urine spots were resuspended in 1 ml pure water, then the amount of urine …

Plasma metabolomic profile in prostatic intraepithelial neoplasia and prostate cancer and associations with the prostate-specific antigen and the Gleason score

PA Markin, A Brito, N Moskaleva, EV Lartsova… - Metabolomics, 2020 - Springer
… Stock solutions at 1 mM were prepared using an aquatic solution of 20 mM sodium bicarbonate
for organic acids; 20 mM hydrochloric acid for amino acids; pure methanol for fatty acids; …

Urinary volatile organic compounds for the detection of prostate cancer

T Khalid, R Aggio, P White, B De Lacy Costello… - PloS one, 2015 - journals.plos.org
acids, organic acids, carbohydrates and fatty acids. Higher levels of the organic acids:
dihydroxybutanoic acid and xylonic acid … were observed in the prostate cancer group. A diagnostic …

Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS

AR Lima, AM Araújo, J Pinto, C Jerónimo… - Scientific reports, 2018 - nature.com
Prostate cancer (PCa) is the second leading cause of cancer-related death in men in most
… markedly influences the prostate cell volatilome (eg detection of volatile organic acids). As …

[PDF][PDF] High dietary acid load is associated with prostate cancer risk: An epidemiological study

AL Ronco, MA Storz, W Martínez-López… - World Cancer Res …, 2021 - wcrj.net
… from metabolism of intestinally absorbed potassium salts of organic acids are central (yet
highly variable) components of the NEAP score21. Both scores were strongly correlated (r=0.84…

Metabolomic signatures of aggressive prostate cancer

JE McDunn, Z Li, KP Adam, BP Neri, RL Wolfert… - … Prostate, 2013 - Wiley Online Library
… in prostate cancer versus cancer-free prostate tissue and … prostate cancer versus less
advanced prostate cancer. This … and organic acids and the majority of amino acids and peptides. …

Non-invasive urinary metabolomic profiling discriminates prostate cancer from benign prostatic hyperplasia

C Pérez-Rambla, L Puchades-Carrasco… - Metabolomics, 2017 - Springer
Prostate cancer (PCa) is one of the most common malignancies in men worldwide. Serum
prostateProstate cancer (PCa) is the most common cancer in men worldwide. The number of …

The role of citric acid in the physiology of the prostate: III. lactate/citrate ratios in benign and malignant prostatic homogenates as an index of prostatic malignancy

JF Cooper, I Farid - The Journal of urology, 1964 - auajournals.org
acid cycle in prostatic tissue, the total organic acidity and individual concentrations of the
organic acid of … Cytologic recognition of early prostatic cancer in prostatic fluid has not been of …