Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer

M Zhao, J Geller, H Ma, M Yang… - Proceedings of the …, 2007 - National Acad Sciences
… shrinkage in mice with sc or orthotopic human breast cancer xerographs. … metastatic human
prostate cancer in orthotopic mouse models, suggesting the clinical potential of this cancer

[HTML][HTML] Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer

D Cunningham, Q Zhang, S Liu… - American Journal of …, 2018 - ncbi.nlm.nih.gov
… Here we report an orthotopic mouse allograft model of prostate cancer that was used to …
Here we report that an orthotopic mouse model was established using mouse prostate cancer

In vivo models of prostate cancer metastasis to bone

AS Singh, WD Figg - The Journal of urology, 2005 - Elsevier
… foci, subcultured the cells and re-injected them back into the mouse model. However, no …
consisted of using GFP labeled PC3 cells in a surgical orthotopic implantation model. …

Viable circulating metastatic cells produced in orthotopic but not ectopic prostate cancer models

AB Glinskii, BA Smith, P Jiang, XM Li, M Yang… - Cancer research, 2003 - AACR
… implanted highly metastatic human prostate cancer at orthotopic and … requirement for
metastasis to many distant sites. Using … nude mouse model for studies of human cancer

Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model

SI Park, J Zhang, KA Phillips, JC Araujo, AM Najjar… - Cancer research, 2008 - AACR
… In orthotopic nude mouse models, dasatinib treatment effectively inhibits expression of …
metastatic potentials of the parental cells determined by an in vivo orthotopic mouse model. …

A fluorescent orthotopic bone metastasis model of human prostate cancer

M Yang, P Jiang, FX Sun, S Hasegawa, E Baranov… - Cancer research, 1999 - AACR
… a spontaneous bone metastasis mouse model of human prostate cancer with the … In this
model, the GFP expression of the SOI-implanted PC-3 cell line enabled metastases to be …

[HTML][HTML] Generation of a syngeneic orthotopic transplant model of prostate cancer metastasis

L Ellis, K Lehet, SY Ku, G Azabdaftari, R Pili - Oncoscience, 2014 - ncbi.nlm.nih.gov
… of metastasis, and more definite pre- clinical therapy trials. Orthotopic murine models have
… and castrate resistant tractable orthotopic murine syngeneic (immune competent) model of …

[HTML][HTML] A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host

BW Simons, V Kothari, B Benzon, K Ghabili… - Oncotarget, 2019 - ncbi.nlm.nih.gov
… few cell lines that metastasize when injected orthotopically [4]… , the metastatic cells in
many transgenic mouse models … Given that majority of clinical cases of prostate cancers are …

Comparative study of subcutaneous and orthotopic mouse models of prostate cancer: vascular perfusion, vasculature density, hypoxic burden and BB2r-targeting …

W Zhang, W Fan, S Rachagani, Z Zhou, SM Lele… - Scientific reports, 2019 - nature.com
… To examine the in vivo BB2r-targeting efficacy and tumor perfusion of the two mouse
models, we performed dual, simultaneous biodistribution studies utilizing the [ 177 Lu]Lu-DOTA-…

Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model

G Canesin, S Evans-Axelsson, R Hellsten… - PLoS …, 2017 - journals.plos.org
… primary tumor and metastasis in vivo and on prostate cancer cell viability, … orthotopic
xenograft mouse model with metastatic luciferase-labeled WNT5A-low DU145 cells and metastatic