CXCR4 inhibition enhances radiosensitivity, while inducing cancer cell mobilization in a prostate cancer mouse model

UM Domanska, JC Boer, H Timmer-Bosscha… - … experimental metastasis, 2014 - Springer
… Irradiation-induced CXCL12 upregulation and consequent recruitment of bone marrow-derived
cells (BMDCs) enhanced tumor vasculogenesis in an orthotopic mouse model of …

A Nod Scid mouse model to study human prostate cancer

C Bastide, C Bagnis, P Mannoni, J Hassoun… - … cancer and prostatic …, 2002 - nature.com
mouse has been used once as a preclinical model for prostate cancer but without orthotopic
… In the present study, the Nod Scid mouse has been used for subcutaneous and orthotopic

A TRAMP‐derived orthotopic prostate syngeneic (TOPS) cancer model for investigating anti‐tumor treatments

J Lardizabal, J Ding, Z Delwar, PS Rennie… - The Prostate, 2018 - Wiley Online Library
… -derived Orthotopic Prostate Syngeneic (TOPS) mouse model was … tumor and metastatic
responses to novel treatments. … novel orthotopic prostate cancer xenograft mouse model named …

[HTML][HTML] The therapeutic efficacy of I131-PSCA-mAb in orthotopic mouse models of prostate cancer

S Yu, F Feng, K Wang, C Men, C Lin, Q Liu… - European Journal of …, 2013 - Springer
… The human prostate cancer models were established by orthotopic implantation of PC-3
and LNCaP cells in nude mice. I 131 -PSCA-mAb distribution and tumor cell apoptosis in the …

Prostate Cancer Treatment is Enhanced by Genistein In Vitro and In Vivo in a Syngeneic Orthotopic Tumor Model

Y Wang, JJ Raffoul, M Che, DR Doerge… - Radiation …, 2006 - meridian.allenpress.com
mouse model were repeated in the RM-9 orthotopic prostate … of LNCaP cells in SCID mice
similar to our model, the soy … Our study in prostate cancer orthotopic models does not address …

Models of prostate cancer bone metastasis

SH Park, MR Eber, Y Shiozawa - Bone Research Protocols, 2019 - Springer
prostate cancer (PCa) experience bone metastasis, which negatively impacts overall survival
and patient quality of life. Various mouse models have … For instance, orthotopic models of …

Combining desmopressin and docetaxel for the treatment of castration-resistant prostate cancer in an orthotopic model

R Bass, D Roberto, DZ Wang, FP Cantu… - Anticancer …, 2019 - ar.iiarjournals.org
orthotopic model, desmopressin treatment was administered by two intravenous injections
covering a 24-h time period following chemotherapy treatment. … -resistant prostate cancer cells …

[HTML][HTML] Targeted alpha therapy in a systemic mouse model of prostate cancer-a feasibility study

AD Stuparu, CAL Meyer, SL Evans-Axelsson… - Theranostics, 2020 - ncbi.nlm.nih.gov
… to establish translatable mouse models of disseminated prostate cancer (… Orthotopic primary
tumors enable response assessments to different therapies. Systemic cancer mouse models

[HTML][HTML] Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

JM Tuomela, MP Valta, K Väänänen, PL Härkönen - BMC cancer, 2008 - Springer
mouse models of cervical cancer [19] and prostate cancer [50]. In addition, both minodronate
and zoledronate affect VEGF interaction with VEGF receptors and signaling in endothelial …

… -mediated interleukin-12 gene therapy for prostate cancer: suppression of orthotopic tumor growth and pre-established lung metastases in an orthotopic model

Y Nasu, CH Bangma, GW Hull, HM Lee, J Hu, J Wang… - Gene therapy, 1999 - nature.com
… Using the RM-9 murine model for prostate we clearly demonstrated significant antitumor
and systemic antimetastatic activities of a single in situ injection of IL-12. It should be …