Inducible shRNA expression for application in a prostate cancer mouse model

F Czauderna, A Santel, M Hinz, M Fechtner… - Nucleic acids …, 2003 - academic.oup.com
… Application of the inducible shRNA expression system in an orthotopic prostate cancer
mouse model. (A) Prostate tumor volume and lymph node metastasis volume of orthotopically

… -mediated interleukin-12 gene therapy for prostate cancer: suppression of orthotopic tumor growth and pre-established lung metastases in an orthotopic model

Y Nasu, CH Bangma, GW Hull, HM Lee, J Hu, J Wang… - Gene therapy, 1999 - nature.com
… Using the RM-9 murine model for prostate we clearly demonstrated significant antitumor
and systemic antimetastatic activities of a single in situ injection of IL-12. It should be …

[HTML][HTML] Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

JM Tuomela, MP Valta, K Väänänen, PL Härkönen - BMC cancer, 2008 - Springer
mouse models of cervical cancer [19] and prostate cancer [50]. In addition, both minodronate
and zoledronate affect VEGF interaction with VEGF receptors and signaling in endothelial …

[HTML][HTML] Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis

D Wong, P Kandagatla, W Korz, SR Chinni - BMC urology, 2014 - Springer
… -9908 in an orthotopic prostate cancer model of primary tumor growth and metastases. The
results … and distant metastases in orthotopic mouse model (Figure 3A), however significant …

Mouse models of prostate cancer

KC Valkenburg, BO Williams - Prostate cancer, 2011 - Wiley Online Library
… as orthotopically into the dorsolateral prostate lobe. Bear in mind that orthotopic implantation
… This model resembled human PCa in that the metastases were found in the lymph node …

Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model

Z Hu, J Gupta, Z Zhang, H Gerseny, A Berg… - Human gene …, 2012 - liebertpub.com
… sTβRFc can be developed as potential new therapies for prostate cancer bone metastasis. …
) in a mouse model of prostate cancer bone metastasis. They show that infection of prostate

Surgical orthotopic implantation allows high lung and lymph node metastatic expression of human prostate carcinoma cell line PC‐3 in nude mice

Z An, X Wang, J Geller, AR Moossa… - The Prostate, 1998 - Wiley Online Library
… lung and lymph node metastasis of human prostate cancer line PC-3 … metastasis from the
orthotopic site after SOI observed in this study still brings this model of human prostate cancer

Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografts via induction of endothelial …

P Sweeney, T Karashima, SJ Kim, D Kedar, B Mian… - Clinical cancer …, 2002 - AACR
… In the present study, using orthotopic models of prostate cancer and prostate cancer
bone metastasis, … transitional cell carcinoma of the bladder in a murine model with the anti-vascular …

Combination gene therapy with adenoviral vector-mediated HSV-tk+ GCV and IL-12 in an orthotopic mouse model for prostate cancer

Y Nasu, CH Bangma, GW Hull, G Yang… - … Cancer and Prostatic …, 2001 - nature.com
… inÆltration of immune cells within orthotopic mouse prostate cancer under single AdHSV-tk
áGCV or AdmIL-12 in situ gene therapy and combined treatment conditions. More extensive …

Model systems of prostate cancer: uses and limitations

NM Navone, CJ Logothetis… - Cancer and metastasis …, 1998 - Springer
… available transgenic mouse models of prostate cancer have … fundamental questions
about the biology of prostate cancer. … ment of a mouse model by using orthotopic (intraprostatic) …