Plasma osteopontin levels in multiple sclerosis

M Comabella, I Pericot, R Goertsches, C Nos… - Journal of …, 2005 - Elsevier
… multiple sclerosis (MS). Here, we investigated the plasma levels of OPN in 221 MS patients
… The MS group comprised of 71 patients with primary and transitional progressive MS (PP/TP…

Osteopontin levels and increased disease activity in relapsing–remitting multiple sclerosis patients

MHJ Vogt, S Floris, J Killestein, DL Knol, M Smits… - Journal of …, 2004 - Elsevier
Osteopontin (OPN) has been identified as the most prominent cytokine-encoding gene
expressed within multiple sclerosis (MS) lesions. Recently, we demonstrated that OPN plasma …

Elevated osteopontin levels in active relapsing‐remitting multiple sclerosis

MHJ Vogt, L Lopatinskaya, M Smits… - Annals of …, 2003 - Wiley Online Library
… protein levels in plasma of relapsing-remitting MS patients. In contrast, OPN protein levels in
… In this study, we demonstrated that RR MS patients had significantly increased OPN levels, …

Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis

M Braitch, R Nunan, G Niepel, LJ Edwards… - Archives of …, 2008 - jamanetwork.com
Osteopontin levels are higher in the serum of MS patients … in OPN levels were found between
patients with relapsing-remitting … Plasma OPN levels are higher in patients with secondary …

Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development

P Kivisäkk, BC Healy, K Francois… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Osteopontin (OPN) is a pleiotropic protein with important roles in inflammation
and immunity that has been suggested as a candidate biomarker for disease activity in …

Plasma osteopontin levels are associated with disease activity in the patients with multiple sclerosis and neuromyelitis optica

Y Shimizu, K Ota, R Ikeguchi, S Kubo… - Journal of …, 2013 - Elsevier
… plasma OPN levels in Japanese multiple sclerosis (MS) and neuromyelitis optica (NMO)
patients to … In NMO patients, plasma OPN levels were significantly higher than those in healthy …

Osteopontin (OPN) as a CSF and blood biomarker for multiple sclerosis: A systematic review and meta-analysis

E Agah, A Zardoui, A Saghazadeh, M Ahmadi… - PLoS …, 2018 - journals.plos.org
… in their CSF compared to patients with stable disease (P = 0.007). The result of this study
confirms that increased levels of OPN exist in CSF and peripheral blood of MS patients and …

Evaluation of plasma Osteopontin level in relapsing-remitting multiple sclerosis patients compared to healthy subjects in Isfahan Province

M Jafarinia, E Sadeghi, F Alsahebfosoul… - International Journal …, 2020 - Taylor & Francis
… OPN level in RRMS patients in … OPN level was significantly higher in RRMS patients in
Isfahan province. Comabella et al. found that plasma OPN level are increased in RRMS patients

Increased osteopontin plasma levels in multiple sclerosis patients correlate with bone-specific markers

MHJ Vogt, J ten Kate, RJM Drent… - Multiple Sclerosis …, 2010 - journals.sagepub.com
… Since osteopontin mRNA levels in peripheral blood mononuclear cells of relapsing-remitting
multiple sclerosis patients did not correlate with osteopontin plasma levels, peripheral …

The role of osteopontin: a shared pathway in the pathogenesis of multiple sclerosis and osteoporosis?

A Altıntaş, G Saruhan-Direskeneli, G Benbir… - Journal of the …, 2009 - Elsevier
… % of MS patients versus 10.3% of controls had osteoporosis (p = 0.017).Osteopontin levels
showed no significant correlation with osteoporosis in controls, but were lower in MS patients