Plasma osteopontin levels in multiple sclerosis
M Comabella, I Pericot, R Goertsches, C Nos… - Journal of …, 2005 - Elsevier
… multiple sclerosis (MS). Here, we investigated the plasma levels of OPN in 221 MS patients
… The MS group comprised of 71 patients with primary and transitional progressive MS (PP/TP…
… The MS group comprised of 71 patients with primary and transitional progressive MS (PP/TP…
Osteopontin levels and increased disease activity in relapsing–remitting multiple sclerosis patients
MHJ Vogt, S Floris, J Killestein, DL Knol, M Smits… - Journal of …, 2004 - Elsevier
Osteopontin (OPN) has been identified as the most prominent cytokine-encoding gene
expressed within multiple sclerosis (MS) lesions. Recently, we demonstrated that OPN plasma …
expressed within multiple sclerosis (MS) lesions. Recently, we demonstrated that OPN plasma …
Elevated osteopontin levels in active relapsing‐remitting multiple sclerosis
MHJ Vogt, L Lopatinskaya, M Smits… - Annals of …, 2003 - Wiley Online Library
… protein levels in plasma of relapsing-remitting MS patients. In contrast, OPN protein levels in
… In this study, we demonstrated that RR MS patients had significantly increased OPN levels, …
… In this study, we demonstrated that RR MS patients had significantly increased OPN levels, …
Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis
M Braitch, R Nunan, G Niepel, LJ Edwards… - Archives of …, 2008 - jamanetwork.com
… Osteopontin levels are higher in the serum of MS patients … in OPN levels were found between
patients with relapsing-remitting … Plasma OPN levels are higher in patients with secondary …
patients with relapsing-remitting … Plasma OPN levels are higher in patients with secondary …
Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development
P Kivisäkk, BC Healy, K Francois… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Osteopontin (OPN) is a pleiotropic protein with important roles in inflammation
and immunity that has been suggested as a candidate biomarker for disease activity in …
and immunity that has been suggested as a candidate biomarker for disease activity in …
Plasma osteopontin levels are associated with disease activity in the patients with multiple sclerosis and neuromyelitis optica
Y Shimizu, K Ota, R Ikeguchi, S Kubo… - Journal of …, 2013 - Elsevier
… plasma OPN levels in Japanese multiple sclerosis (MS) and neuromyelitis optica (NMO)
patients to … In NMO patients, plasma OPN levels were significantly higher than those in healthy …
patients to … In NMO patients, plasma OPN levels were significantly higher than those in healthy …
Osteopontin (OPN) as a CSF and blood biomarker for multiple sclerosis: A systematic review and meta-analysis
… in their CSF compared to patients with stable disease (P = 0.007). The result of this study
confirms that increased levels of OPN exist in CSF and peripheral blood of MS patients and …
confirms that increased levels of OPN exist in CSF and peripheral blood of MS patients and …
Evaluation of plasma Osteopontin level in relapsing-remitting multiple sclerosis patients compared to healthy subjects in Isfahan Province
… OPN level in RRMS patients in … OPN level was significantly higher in RRMS patients in
Isfahan province. Comabella et al. found that plasma OPN level are increased in RRMS patients …
Isfahan province. Comabella et al. found that plasma OPN level are increased in RRMS patients …
Increased osteopontin plasma levels in multiple sclerosis patients correlate with bone-specific markers
MHJ Vogt, J ten Kate, RJM Drent… - Multiple Sclerosis …, 2010 - journals.sagepub.com
… Since osteopontin mRNA levels in peripheral blood mononuclear cells of relapsing-remitting
multiple sclerosis patients did not correlate with osteopontin plasma levels, peripheral …
multiple sclerosis patients did not correlate with osteopontin plasma levels, peripheral …
The role of osteopontin: a shared pathway in the pathogenesis of multiple sclerosis and osteoporosis?
A Altıntaş, G Saruhan-Direskeneli, G Benbir… - Journal of the …, 2009 - Elsevier
… % of MS patients versus 10.3% of controls had osteoporosis (p = 0.017).Osteopontin levels
showed no significant correlation with osteoporosis in controls, but were lower in MS patients …
showed no significant correlation with osteoporosis in controls, but were lower in MS patients …
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