Clinical impact of recent genetic discoveries in osteoporosis

BD Mitchell, EA Streeten - The Application of Clinical Genetics, 2013 - Taylor & Francis
fracture risk in osteoporosis, with an emphasis on genetic factors, and to discuss the potential
impact of new genetic … at risk for osteoporotic fracture and preventing future fractures. …

The genetic architecture of osteoporosis and fracture risk

K Trajanoska, F Rivadeneira - Bone, 2019 - Elsevier
… also associated with osteoporotic fractures, reproducing the … with BMD and osteoporotic
fractures. Subsequent work by the … Target Genes may have substantial impact on bone biology. …

[PDF][PDF] Epidemiology of osteoporotic fracture: looking to the future

C Cooper - Rheumatology-Supplements, 2005 - Citeseer
… to genetic predisposition, candidate genes, the evolving area of intrauterine fetal
programming, environmental factors and the fascinating glimpses of interactions between genetic

The influence of the genetic and non-genetic factors on bone mineral density and osteoporotic fractures in Chinese women

YH Deng, L Zhao, MJ Zhang, CM Pan, SX Zhao… - Endocrine, 2013 - Springer
… 18 SNPs and non-genetic factors with BMDs and osteoporotic fractures in 1012 Chinese Han
… the combined effect of genetic and non-genetic factors on the risk of osteoporotic fractures. …

[HTML][HTML] Recent advances in the genetics of fractures in osteoporosis

F Koromani, K Trajanoska, F Rivadeneira… - Frontiers in …, 2019 - frontiersin.org
… of genetic determinants of fracture risk. We first discuss the genetic architecture of fracture
… review touches upon potential future directions in genetic research of osteoporotic fractures. …

Genetic liability to fractures in the elderly

K Michaëlsson, H Melhus, H Ferm… - Archives of internal …, 2005 - jamanetwork.com
genetic impact on the causation of osteoporotic fractures is unclear. A large twin study is ideally
suited to determine the genetic liability to categories of fracturegenetic liability to fracture

[HTML][HTML] An insight into the paradigms of osteoporosis: From genetics to biomechanics

F Al Anouti, Z Taha, S Shamim, K Khalaf, L Al Kaabi… - Bone reports, 2019 - Elsevier
… , metabolic and environmental factors, with severe impact on … , genetic and biomechanical
aspects of primary osteoporosis. … to osteoporotic fractures, 25%–54% for fractures of the wrist, …

Genetic impact of vitamin D receptor TaqI polymorphism on the risk of osteoporotic fractures in diabetic patients

NM Abdelmaksoud, AI Abulsoud, MI Abulsoud… - Gene Reports, 2022 - Elsevier
… idiopathic osteoporotic fractures and secondary T2DM osteoporotic fractures. Moreover, AG
(Tt) genotype was significantly found in secondary T2DM osteoporotic fractures compared to …

Genetic factors and osteoporotic fractures in elderly people: prospective 25 year follow up of a nationwide cohort of elderly Finnish twins

P Kannus, M Palvanen, J Kaprio, J Parkkari… - Bmj, 1999 - bmj.com
… , the impact energy created by the fall, and the capacity of the soft tissues around the impact
site … and quantity are the main determinants of the fracture, and it is easy to understand that …

[HTML][HTML] Major osteoporotic fragility fractures: Risk factor updates and societal impact

P Pisani, MD Renna, F Conversano… - World journal of …, 2016 - ncbi.nlm.nih.gov
impact of osteoporotic fractures on population. Because early diagnosis is the key to reduce
the impact of osteoporosis on … might be important and there is some evidence for a genetic