MicroRNAs in ovarian cancer biology and therapy resistance
MTM van Jaarsveld, J Helleman, EMJJ Berns… - The international journal …, 2010 - Elsevier
… The management of ovarian cancer has improved over the last 20 years due to more effective
… These studies suggest that targeting of let-7 in ovarian cancer is feasible and might lead to …
… These studies suggest that targeting of let-7 in ovarian cancer is feasible and might lead to …
Role of microRNAs in drug-resistant ovarian cancer cells
A Sorrentino, CG Liu, A Addario, C Peschle… - Gynecologic …, 2008 - Elsevier
… of advanced ovarian cancer, but a successful long-term treatment is prevented by … non-coding
RNAs, microRNAs (miRNAs) in cancer development, with several … miRNA target prediction …
RNAs, microRNAs (miRNAs) in cancer development, with several … miRNA target prediction …
MicroRNA‐mediated drug resistance in ovarian cancer
A Mihanfar, A Fattahi… - Journal of cellular …, 2019 - Wiley Online Library
… markers, as well as novel therapeutic targets to overcome resistance in ovarian cancer. …
(MDR) is one of the main hurdles against successful and complete treatment of ovarian cancer. …
(MDR) is one of the main hurdles against successful and complete treatment of ovarian cancer. …
[HTML][HTML] The potential of MicroRNAs as clinical biomarkers to aid ovarian cancer diagnosis and treatment
… This research is still at a preliminary stage, and although initial studies are important in order
to identify candidate miRNA targets for investigation, the small sample sizes often bring the …
to identify candidate miRNA targets for investigation, the small sample sizes often bring the …
[HTML][HTML] Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine
… profiling of miRNAs can be employed for the clinical management of OC. … and cancer
dissemination by targeting MTDH (metadherin) in HGSOCs (high grade serous ovarian cancer) via …
dissemination by targeting MTDH (metadherin) in HGSOCs (high grade serous ovarian cancer) via …
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
R Rupaimoole, FJ Slack - Nature reviews Drug discovery, 2017 - nature.com
… cancer types, including neuroblastoma, ovarian cancer … ovarian cancer, an integrated
network analysis of potential mRNA target expression revealed miR-506 as one of the miRNAs …
network analysis of potential mRNA target expression revealed miR-506 as one of the miRNAs …
Tumor-targeting, microRNA-silencing porous silicon nanoparticles for ovarian cancer therapy
… To our knowledge, this is the first report of effective in vivo treatment of ovarian cancer
leveraging an anti-miR-21 therapeutic agent. Looking forward, more complex models of …
leveraging an anti-miR-21 therapeutic agent. Looking forward, more complex models of …
[HTML][HTML] Epigenetic biomarkers in the management of ovarian cancer: current prospectives
… miRNA signatures that could distinguish ovarian tumors … prognostic relevance of several
miRNAs, their association with … well as therapeutic target for ovarian cancer management. For …
miRNAs, their association with … well as therapeutic target for ovarian cancer management. For …
Updates and current challenges in microRNA research for personalized medicine in ovarian cancer
V Mandilaras, M Vernon… - Expert Opinion on …, 2017 - Taylor & Francis
… miRNAs is an innovative and promising field for the diagnosis and treatment of ovarian cancer…
, each mRNA may be targeted by several different miRNAs, leading to complex regulatory …
, each mRNA may be targeted by several different miRNAs, leading to complex regulatory …
MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer
N Yang, S Kaur, S Volinia, J Greshock, H Lassus… - Cancer research, 2008 - AACR
… , and treatment of this disease. Here, we used miRNA microarray on 69 ovarian tumor
specimens to identify the … Up to one-third of human mRNAs seem to be miRNA targets (41). Each …
specimens to identify the … Up to one-third of human mRNAs seem to be miRNA targets (41). Each …