miRNAs and ovarian cancer: a miRiad of mechanisms to induce cisplatin drug resistance

P Samuel, RC Pink, SA Brooks… - Expert review of …, 2016 - Taylor & Francis
… to be employed for the treatment of ovarian cancer and most studies addressing the …
the sensitivity of ovarian cancer cells to cisplatin and in which the target mRNAs have been …

MicroRNA-based signatures impacting clinical course and biology of ovarian cancer: a miRNOmics study

E Krasniqi, A Sacconi, D Marinelli, L Pizzuti… - Biomarker …, 2021 - Springer
… Novel biomarkers of early diagnosis, prognosis definition and prediction of treatment
analysis using predicted/validated miRNA target genes, followed by network representation of the …

Detection of microRNA as novel biomarkers of epithelial ovarian cancer from the serum of ovarian cancer patient

YW Chung, HS Bae, JY Song, JK Lee… - … of Gynecologic Cancer, 2013 - ijgc.bmj.com
… patients had not received any definitive treatment at the time of serum sampling. None of the
… -regulation in 1 cancer patient, we included miR145 as a target miRNA because it is widely …

microRNA and the pathogenesis of ovarian cancer-a new horizon for molecular diagnostics and treatment?

JD Kuhlmann, J Rasch, P Wimberger… - Clinical Chemistry & …, 2012 - search.ebscohost.com
… modulate miRNA expression in cancer and try to assess how miRNA … and the clinical
management of ovarian cancer. … in miRNA sequences but also in a miRNA target sites have been …

microRNAs as biomarkers of ovarian cancer

H Zhang, B Lu - Expert Review of Anticancer Therapy, 2020 - Taylor & Francis
… suppressor miR-6126 into TME is critical for OC metastasis; thereby providing a potential
therapeutic target in ovarian cancer treatment. Increased miR-205 expression and circulating …

Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response

D Liang, L Meyer, DW Chang, J Lin, X Pu, Y Ye, J Gu… - Cancer research, 2010 - AACR
… mRNA transcripts might be miRNA targets (4). The involvement of … of miRNA-related genes
might modulate ovarian cancer risk. In this report, we investigated 238 SNPs from 8 miRNA

ROS and miRNA dysregulation in ovarian cancer development, angiogenesis and therapeutic resistance

DC Stieg, Y Wang, LZ Liu, BH Jiang - International Journal of Molecular …, 2022 - mdpi.com
treatment options. Ovarian cancer (OC) is among the most difficult cancers to treat. OC has
limited … Most human miRNAs function as tumor suppressors by directly targeting and inhibiting …

A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer

X Hu, DM Macdonald, PC Huettner, Z Feng… - Gynecologic …, 2009 - Elsevier
treatment decisions for ovarian cancer. However, it has been well known that ovarian tumors
with … Our miRNA target analysis further suggests that miR-200s could potentially reduce cell …

MicroRNA let-7a: a potential marker for selection of paclitaxel in ovarian cancer management

L Lu, P Schwartz, L Scarampi, T Rutherford… - Gynecologic …, 2011 - Elsevier
cancer cells to platinum, but induce ovarian cancer resistance to paclitaxel. This study aims
to investigate the effect of let-7a expression on survival outcomes of epithelial ovarian cancer

miRNA profiling along tumour progression in ovarian carcinoma

O Vaksman, HT Stavnes, J Kærn… - Journal of cellular …, 2011 - Wiley Online Library
… An additional miRNA target we studied was the tumour suppressor phosphatase and
tensin homologue deleted on chromosome 10 (PTEN), a negative regulator of the …