[HTML][HTML] Roles of microRNAs in ovarian cancer tumorigenesis: two decades later, what have we learned?
AA Alshamrani - Frontiers in oncology, 2020 - frontiersin.org
… the aberrant expression of miRNAs and their targeted genes drives ovarian cancer initiation,
… a strong potential to serve as a therapeutic approach for the treatment of ovarian cancer. …
… a strong potential to serve as a therapeutic approach for the treatment of ovarian cancer. …
MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
H Yang, W Kong, L He, JJ Zhao, JD O'Donnell, J Wang… - Cancer research, 2008 - AACR
… recurs in most patients within 3 years following treatment due to the development of
chemoresistance (23). Having shown that miR-214 is involved in cisplatin resistance in …
chemoresistance (23). Having shown that miR-214 is involved in cisplatin resistance in …
[HTML][HTML] Identifying microRNA/mRNA dysregulations in ovarian cancer
… of microRNA therapies in treating ovarian cancers. The positively correlated microRNA/…
have been identified in various studies [5–15], regulatory mRNA targets of microRNA have …
have been identified in various studies [5–15], regulatory mRNA targets of microRNA have …
[PDF][PDF] Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer
… A set of 219 genes was predicted to be targeted by 19 miRNAs (Figure 1; see also Table S1
… Interestingly, we performed a demethylation experiment by treating ovarian cancer cells with …
… Interestingly, we performed a demethylation experiment by treating ovarian cancer cells with …
… –mesenchymal transition-associated miRNAs in ovarian carcinoma, with highlight on the miR-200 family: Prognostic value and prospective role in ovarian cancer …
M Koutsaki, DA Spandidos, A Zaravinos - Cancer letters, 2014 - Elsevier
… Thus, the discovery of validated miRNA targets is of great importance. … of carboplatin–paclitaxel
has been adapted as the standard treatment for women with advanced EOC [98]. …
has been adapted as the standard treatment for women with advanced EOC [98]. …
A prognostically relevant miRNA signature for epithelial ovarian cancer
DW Cramer, KM Elias - The Lancet Oncology, 2016 - thelancet.com
… in the derivation of prognostic miRNA signatures for ovarian cancer, the model has … miRNAs
shared among all three platforms. This is but a fraction of the predicted number of miRNAs in …
shared among all three platforms. This is but a fraction of the predicted number of miRNAs in …
[HTML][HTML] MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells
M Moghbeli - Journal of ovarian research, 2021 - Springer
… miRNAs based on their targets to clarify their probable molecular mechanisms during cisplatin
resistance in ovarian tumor … OC cells to DDP-treatment via mTOR targeting [55]. The mTOR…
resistance in ovarian tumor … OC cells to DDP-treatment via mTOR targeting [55]. The mTOR…
[HTML][HTML] Ovarian cancer: molecular classification and targeted therapy
F Ravindran, B Choudhary - Ovarian Cancer-Updates in Tumour …, 2021 - intechopen.com
… of miRNAs in chemoresistance and sensitivity in the regulation of ovarian cancer. … Changing
the paradigm in the treatment of platinum-sensitive recurrent ovarian cancer: from platinum …
the paradigm in the treatment of platinum-sensitive recurrent ovarian cancer: from platinum …
[HTML][HTML] MicroRNA-mRNA functional pairs for cisplatin resistance in ovarian cancer cells
M Liu, X Zhang, CF Hu, Q Xu, HX Zhu… - … Journal of Cancer, 2014 - ncbi.nlm.nih.gov
… The most commonly employed chemotherapeutic drug for ovarian cancer treatment is cisplatin.
… Current bioinformatics methods for predicting miRNA targets provide large numbers of …
… Current bioinformatics methods for predicting miRNA targets provide large numbers of …
Optimizing molecular‐targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways
D Hiss - Journal of oncology, 2012 - Wiley Online Library
… The optimal management modality for ovarian cancer … of miRNA-200 family members in
ovarian tumors obtained from … based treatment; some miRNAs have been identified as putative …
ovarian tumors obtained from … based treatment; some miRNAs have been identified as putative …