… Additional target analysis indicated that these miRNAs target multiple genes that are … at
the same time, targeting a single miRNA may be not sufficient for treatment. For this reason, …

… 90 days treatment with … miRNA to a target miRNA always occurs in the presence of an Ago
protein. Base-pairing between nucleotides 2 and 8 of an miRNA and its cognate miRNA target …

… progression of ovarian cancer, we profiled miRNAs and their target genes in serous epithelial
… -promoting genes has potential as a cancer treatment (50), although this approach has …

… , by complementary binding with targets on messenger-RNAs (… A single miRNA can have
multiple target genes, and … as first-line treatment for patients with ovarian cancer: the MITO-2 …

… index combination of the risk of malignancy index, risk of ovarian malignancy algorithm
and OV A1 has been approved by Food and Drug Administration for clinical use. In terms of …

… and attempt to clarify their role in early diagnosis, prognosis, and response to treatment. …
The BRCA1/2 reversion mutation status was also assessed by using targeted massively parallel …

… in ovarian cancer (OC) microenvironment, we performed RPPA as well as many other in vitro
functional assays in ovarian cancer cells (… The standard management of ovarian cancer is a …

… as the most promising targeted therapy for ovarian cancer. In the United States, the FDA
approved olaparib for maintenance treatment of patients with BRCA MUT advanced epithelial …

… The quantification of deregulated levels of microRNAs could facilitate earlier diagnosis and
… This microRNA panel may be promising molecules to be targeted in the treatment of EOC. …

… targets form an obstacle in the treatment of ovarian cancer [4]. … role of miRNA-101 as the
tumor suppressor in ovarian cancer. … miRNA-101 is aberrantly downregulated in ovarian cancer …