… This review focuses on the role of aromatase, ovarian steroids and stem-progenitor cells
in the pathogenesis of uterine leiomyoma, and discusses the therapeutic implications of the …

… It is widely accepted that the growth of uterine leiomyomas is up-regulated by estrogen and
its receptors (ERα, ERβ), … The ovary is thought to be the major source of sex steroids for …

… embolization that could lead to premature ovarian failure is limited but not negligible. The …
One potential link between the effects of the 2 key steroid hormones on Uterine leiomyomas …

… Furthermore, to understand the role of progesterone in regulating proliferative activity of
leiomyoma cells, we examined whether ovarian steroids could influence PCNA expression in …

… role of ovarian steroids in regulating proliferative activity of leiomyoma cells, we examined
whether ovarian steroids could influence PCNA expression in cultured leiomyoma cells. Since …

… The role of ovarian steroid hormones in the pathogenesis of uterine fibroids is supported by
… of steroid hormones in the pathogenesis of uterine fibroids as depicted by in vitro studies. …

… role of steroid hormones in the pathogenesis of uterine leiomyoma have … In the Eker rat
model for uterine leiomyoma, tumor … of ovarian steroid hormones in the development of uterine …

… Uterine leiomyomas develop during the reproductive years and regress after menopause,
indicating ovarian steroid‐dependent growth potential. Although the clinical and biochemical …

… uterine bleeding, large pelvic masses, and recurrent pregnancy loss. Although the dependency
of UL growth on ovarian steroids … To elucidate the functions of ovarian steroids in UL, we …

… and growth of uterine leiomyoma. Our results suggest that ovarian steroid hormones increase
… decrease PRT and PRB mRNA levels in uterine leiomyoma cells. Moreover, HDAC activity …