[PDF][PDF] Why are women with polycystic ovary syndrome obese?

TM Barber - British Medical Bulletin, 2022 - academic.oup.com
… of epigenetic factors and the developmental origins of PCOS. … associate with polycystic ovary
syndrome: prospective cohort … loss in obese women with polycystic ovary syndrome. J Clin …

[HTML][HTML] Polycystic ovary syndrome: a comprehensive review of pathogenesis, management, and drug repurposing

HM Sadeghi, I Adeli, D Calina, AO Docea… - International journal of …, 2022 - mdpi.com
… Although the pathogenesis of PCOS is not fully understood, it is believed that different
factors from epigenetic alterations to obesity, inflammation, and inactivity may aggravate this …

Perspectives in polycystic ovary syndrome: from hair to eternity

A Dunaif - The Journal of Clinical Endocrinology & Metabolism, 2016 - academic.oup.com
… Future studies should clarify the contribution of rare genetic variants and epigenetic factors
… It is particularly timely to consider the disorder currently known as polycystic ovary syndrome (…

Deciphering the DNA methylome of polycystic ovary syndrome

Q Tan - Molecular Diagnosis & Therapy, 2020 - Springer
Epigenetic studies help to elucidate the intricate interplay between the genome and the
environment in polycystic ovary syndrome … due to multiple factors, including limitations in …

[HTML][HTML] Androgen-induced epigenetic modulations in the ovary

I Salinas, N Sinha, A Sen - Journal of Endocrinology, 2021 - joe.bioscientifica.com
… While high levels of androgens in women are associated with polycystic ovary syndrome (…
be one of the contributing factors to ovarian and metabolic dysfunction associated with PCOS. …

[HTML][HTML] A single bout of electroacupuncture remodels epigenetic and transcriptional changes in adipose tissue in polycystic ovary syndrome

M Kokosar, A Benrick, A Perfilyev, E Nilsson… - Scientific Reports, 2018 - nature.com
ovary syndrome (PCOS) is a common heritable disorder of unclear etiology. Genetic and
epigenetic factors … , has been demonstrated to be a strong factor in the development of insulin …

[HTML][HTML] The epigenetic correlation among ovarian cancer, endometriosis and PCOS: A review

HT PK, L Unnikrishnan, M Pangath… - Critical reviews in …, 2022 - Elsevier
Epigenetic factors have shown to be an important reason for cancer progression. Our findings
at the epigenetic … have an important role in polycystic ovary syndrome (Goodman et al.) …

[HTML][HTML] Epigenetic regulation of an adverse metabolic phenotype in polycystic ovary syndrome: the impact of the leukocyte methylation of PPARGC1A promoter

H Zhao, Y Zhao, Y Ren, M Li, T Li, R Li, Y Yu, J Qiao - Fertility and Sterility, 2017 - Elsevier
Objective To investigate PPARGC1A promoter methylation and mitochondria DNA (mtDNA)
content in the leukocytes of women with polycystic ovary syndrome (PCOS) and analyze the …

The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic‐Cytoprotective Adjuvant Therapy

E Spinedi, DP Cardinali - International journal of endocrinology, 2018 - Wiley Online Library
factor for insulin resistance in polycystic ovary syndrome. … /epigenetic factors may also
play relevant roles in syndromeovary syndrome, thus suggesting that some polycystic ovary

Thymoquinone reduces intracytoplasmic oxidative stress and improves epigenetic modification in polycystic ovary syndrome mice oocytes, during in‐vitro maturation

F Eini, A Bidadkosh, H Nazarian… - Molecular …, 2019 - Wiley Online Library
… (TQ) during IVM in the polycystic ovary syndrome (PCOS) mice model. The induction of …
disorders and affect epigenetic modification. It was also shown that these factors hamper the …