Characterization of DNA methylation and screening of epigenetic markers in polycystic ovary syndrome
P Cao, W Yang, P Wang, X Li… - Frontiers in cell and …, 2021 - frontiersin.org
… , we focused on ovarian GCs to investigate the epigenetic regulatory mechanism of PCOS. …
methylation characteristics and screened potential epigenetic markers. We identified several …
methylation characteristics and screened potential epigenetic markers. We identified several …
Polycystic ovary syndrome: the epigenetics behind the disease
MC Eiras, DP Pinheiro, KAM Romcy, RA Ferriani… - Reproductive …, 2022 - Springer
… Altered DNA methylation is the main reported epigenetic marker in developmental epigenetic
reprogramming of PCOS. These modifications lead to gene silencing or reduction of its …
reprogramming of PCOS. These modifications lead to gene silencing or reduction of its …
Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment
E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
… is germline transmission of epigenetic markers. Intergenerational and transgenerational …
, as the whole ovary was sequenced in this study, whether these effects result from epigenetic …
, as the whole ovary was sequenced in this study, whether these effects result from epigenetic …
Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors
D Szukiewicz, S Trojanowski, A Kociszewska… - International journal of …, 2022 - mdpi.com
… patients, elevated values of inflammatory markers or their gene markers have been reported.
… Epigenetic modulation of androgenic activity in response to inflammatory signaling is also …
… Epigenetic modulation of androgenic activity in response to inflammatory signaling is also …
[HTML][HTML] Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura… - Cell metabolism, 2021 - cell.com
… of DNA methylation and propose methylome markers as a possible diagnostic landmark
for the condition, while also identifying potential candidates for epigenetic-based therapy. …
for the condition, while also identifying potential candidates for epigenetic-based therapy. …
[PDF][PDF] Role of epigenetic modifications in the aberrant CYP19A1 gene expression in polycystic ovary syndrome
E Hosseini, M Shahhoseini, P Afsharian… - Archives of Medical …, 2019 - termedia.pl
… infertile polycystic ovary syndrome (PCOS) patients and the correlation of these epigenetic
modifications with the expression of the ovarian aromatase gene (as an important marker in …
modifications with the expression of the ovarian aromatase gene (as an important marker in …
Epigenetic marks in polycystic ovary syndrome
AB Motta - Current Medicinal Chemistry, 2020 - ingentaconnect.com
… Moreover, the determination of genetic markers may increase the … markers available to
date. Thus, the aim of this review is to provide updated information on these epigenetic marks (mi…
date. Thus, the aim of this review is to provide updated information on these epigenetic marks (mi…
Deciphering the DNA methylome of polycystic ovary syndrome
Q Tan - Molecular Diagnosis & Therapy, 2020 - Springer
… PCOS from disease etiology to epigenetic marker discovery. Current epigenetic studies have
provided convincing observational evidence linking epigenetic regulation with PCOS origin…
provided convincing observational evidence linking epigenetic regulation with PCOS origin…
Polycystic ovary syndrome-epigenetic mechanisms and aberrant microRNA
IR Ilie, CE Georgescu - Advances in clinical chemistry, 2015 - Elsevier
… the clinical presentation via epigenetic modifications. MicroRNA (… This review examines the
role of epigenetics and miRNA in the … increased expression of the proliferation marker PCNA. …
role of epigenetics and miRNA in the … increased expression of the proliferation marker PCNA. …
DNA methylation in the pathogenesis of polycystic ovary syndrome
ER Vázquez-Martínez, YI Gómez-Viais… - …, 2019 - rep.bioscientifica.com
… (and other epigenetic marks) in the peripheral blood is the fact that the total DNA is isolated
from different cell types with their DNA methylation profile, whose content and epigenetic …
from different cell types with their DNA methylation profile, whose content and epigenetic …
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