Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data

S Michiels, A Le Maître, M Buyse, T Burzykowski… - The lancet …, 2009 - thelancet.com
… control and EFS were strongly correlated with those on overall survival (R=0·94 and 0·98, …
overall survival were stronger than those between locoregional control and overall survival (…

[HTML][HTML] Individual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern …

Q Shi, A De Gramont, A Grothey… - Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Purpose Progression-free survival (PFS) has previously been established as a surrogate for
overall survival (OS) for first-line metastatic colorectal cancer (mCRC). Because mCRC …

Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized …

DJ Sargent, HS Wieand, DG Haller, R Gray… - Journal of Clinical …, 2005 - ascopubs.org
… A traditional end point for colon adjuvant clinical trials is overall survival (OS), with 5 years
Individual patient data were pooled from 18 randomized phase III colon cancer adjuvant …

… for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data

A Mauguen, JP Pignon, S Burdett, C Domerg… - The lancet …, 2013 - thelancet.com
… endpoints and overall survival at individual and trial levels. … DFS and overall survival were
very good at the individual level … and overall survival were very good at the individual level (ρ 2 …

… , disease progression, and overall survival after dabrafenib and trametinib combination treatment: a pooled analysis of individual patient data from randomised trials

GV Long, JJ Grob, P Nathan, A Ribas, C Robert… - The lancet …, 2016 - thelancet.com
progression-free survival and overall survival in patients with BRAF V600 -mutant melanoma,
although the degree of treatment benefit varied. Studies of small groups of patients treated …

Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
… to determine the pooled overall treatment effect on OS of … patients with newly diagnosed
EGFR-mutated advanced NSCLC using individual patient data from RCTs with updated survival

[PDF][PDF] Individual-level data on the relationships of progression-free survival, post-progression survival, and tumor response with overall survival in patients with …

H Imai, T Takahashi, K Mori, A Ono, H Akamatsu… - Neoplasma, 2014 - academia.edu
… in patients with non-small cell lung cancer (NSCLC). We examined whether progression-free
survival (PFS), post-progression survival (… NSCLC by using individual-level data, given the …

Surrogate end points for overall survival in loco-regionally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis

F Rotolo, JP Pignon, J Bourhis… - JNCI: Journal of the …, 2017 - academic.oup.com
Background: The 21-gene recurrence score (RS) predicts risk of locoregional recurrence (LRR)
in node-negative, estrogen receptor (ER)–positive breast cancer. We evaluated the …

[HTML][HTML] A review of studies examining the relationship between progression-free survival and overall survival in advanced or metastatic cancer

S Davis, P Tappenden, A Cantrell - 2017 - europepmc.org
… PFS and OS for individual trial arms. Seven studies used individual patient data to examine
the relationship between PFS and OS for individual patients. Thirteen studies examined the …

[HTML][HTML] Rituximab maintenance improves overall survival of patients with follicular lymphoma—individual patient data meta-analysis

L Vidal, A Gafter-Gvili, G Salles, S Bousseta… - European Journal of …, 2017 - Elsevier
survival has been inconclusive. To evaluate the effect of MR on overall survival according to
patient … certain adverse events, we performed an individual patient data (IPD) meta-analysis. …