Impact of systemic treatment on survival after whole brain radiotherapy in patients with brain metastases

C Nieder, K Marienhagen, A Dalhaug, G Aandahl… - Medical Oncology, 2014 - Springer
… The influence on overall survival was not significant (7 vs. 8.6 months). A second … Overall
survival and response rates were similar, while progression-free survival at 90 days was better …

[HTML][HTML] Whole brain radiotherapy for brain metastasis

E McTyre, J Scott, P Chinnaiyan - Surgical neurology international, 2013 - ncbi.nlm.nih.gov
… A recent study completed by the EORTC demonstrated both a decreased risk of developing
brain metastasis and improvement in overall survival at one year in patients receiving PCI.[76…

[PDF][PDF] Overall survival and related prognostic factors in metastatic brain tumors treated with whole brain radiation therapy

ASY Kashi, B Mofid, HR Mirzaei, P Azadeh - Neurosurgery, 2010 - academia.edu
… treated with surgery followed by whole brain radiotherapy had better survival. This data suggest
that … to the brain may be treated effectively with surgical resection plus radiotherapy. The …

Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer

AT Karlsson, MJ Hjermstad, T Omdahl, N Aass… - Acta …, 2021 - Taylor & Francis
Full article: Overall survival after initial radiotherapy for brain metastases; a … Overall, studies
report no difference in overall survival (OS) comparing SRT to whole-brain radiotherapy

Radiosurgery for brain metastases: is whole brain radiotherapy necessary?

PK Sneed, KR Lamborn, JM Forstner… - … Journal of Radiation …, 1999 - Elsevier
Whole brain radiotherapy is widely applicable and technically easy to deliver; it … with brain
metastases and improves median survival to 3–6 months compared with a median survival of …

[HTML][HTML] Combination of whole-brain radiotherapy with epidermal growth factor receptor tyrosine kinase inhibitors improves overall survival in EGFR-mutated non …

CH Chen, HH Lee, HY Chuang, JY Hung, MY Huang… - Cancers, 2019 - mdpi.com
… and withholding of whole-brain radiation therapy (WBRT) is controversial. We aim to investigate
the impact of WBRT on overall survival (OS). After screening 1384 patients, a total of 141 …

[HTML][HTML] Whole-brain radiotherapy for brain metastases: evolution or revolution?

PD Brown, MS Ahluwalia, OH Khan… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
… metastases by more than half, as well as death from neurologic causes; however, these
benefits have not been shown to translate into an overall survival prolongation, recognizing that …

A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases

PK Sneed, JH Suh, SJ Goetsch, SN Sanghavi… - … Journal of Radiation …, 2002 - Elsevier
… For decades, the standard treatment for most patients with brain metastases has been whole
brain radiotherapy (WBRT), resulting in symptomatic improvement in a majority of patients (…

Could time of whole brain radiotherapy delivery impact overall survival in patients with multiple brain metastases?

S Chan, L Rowbottom, R McDonald… - Annals of palliative …, 2016 - apm.amegroups.org
… to treat brain metastases. Previous studies have explored how radiotherapy treatment time
… The present study evaluated the influence of treatment time on overall survival (OS) for …

Brain metastasis velocity: a novel prognostic metric predictive of overall survival and freedom from whole-brain radiation therapy after distant brain failure following …

M Farris, ER McTyre, CK Cramer, R Hughes… - … Journal of Radiation …, 2017 - Elsevier
… of development of new brain metastases after initial stereotactic … overall survival following
distant brain failure and was associated with decreased rates of salvage whole-brain radiation