Acute hypoxia modulates 5-HT receptor density and agonist affinity in fetal and adult ovine carotid arteries
DM Angeles, J Williams, L Zhang… - American Journal of …, 2000 - journals.physiology.org
… In our ovine carotid arteries, receptor density was clearly depressed after 30 min of exposure
to hypoxia, suggesting that at this time receptor recovery was depressed relative to the rate …
to hypoxia, suggesting that at this time receptor recovery was depressed relative to the rate …
Effects of maturation and acute hypoxia on receptor-IP3 coupling in ovine common carotid arteries
DM Angeles, J Williams, RE Purdy… - American Journal …, 2001 - journals.physiology.org
… agonist affinity, at least for serotonin in ovine carotid arteries (4). Thus the experimental
approach we adopted was designed to emphasize differences in receptor gain independent of …
approach we adopted was designed to emphasize differences in receptor gain independent of …
Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries
RB Thorpe, SL Stockman, JM Williams… - American Journal …, 2013 - journals.physiology.org
… All common carotid arteries used in this study were harvested … adult sheep. In normoxic
animals maintained at sea level … and agonist affinity in fetal and adult ovine carotid arteries. …
animals maintained at sea level … and agonist affinity in fetal and adult ovine carotid arteries. …
Competing Effects Among Protein Kinase G, Chronic Hypoxia, and Postnatal Maturation on 5HT Agonist Affinity in Ovine Carotid Cerebral Arteries
WJ Pearce, JM Williams - 2008 - Wiley Online Library
… competing changes in agonist binding affinity at the … carotid arteries were qualitatively
different: PM decreased pKa, CH increased pKa in fetal arteries but decreased it in adult arteries…
different: PM decreased pKa, CH increased pKa in fetal arteries but decreased it in adult arteries…
Pre- and postjunctional α2-adrenergic receptors in fetal and adult ovine cerebral arteries
JM Bishai, L Penninga, R Nijland… - American Journal …, 2002 - journals.physiology.org
… adult sheep, we measured α 2 -AR density and affinity with … in arterial contractility to NE and/or
other agonists is agonist/… cerebral and common carotid arteries of the adult sheep (22) and …
other agonists is agonist/… cerebral and common carotid arteries of the adult sheep (22) and …
Effects of maturation, artery size, and chronic hypoxia on 5-HT receptor type in ovine cranial arteries
GQ Teng, J Williams, L Zhang… - American Journal of …, 1998 - journals.physiology.org
… determined relative agonist potency orders and antagonist affinities in common carotid (Com)…
(2BR) arteries from term fetal lambs and nonpregnant adult sheep acclimatized at sea level …
(2BR) arteries from term fetal lambs and nonpregnant adult sheep acclimatized at sea level …
ERK inhibition attenuates 5-HT-induced contractions in fetal and adult ovine carotid arteries
WJ Pearce, JM Williams, MM Chang… - Archives of physiology …, 2003 - Taylor & Francis
… contribute differently to development of agonist-induced contractile force in immature and
mature … receptor density and binding affinity tend to be greater in fetal than adult ovine common …
mature … receptor density and binding affinity tend to be greater in fetal than adult ovine common …
Effects of maturation on alpha-adrenergic receptor affinity and occupancy in small cerebral arteries
SR Elliott, WJ Pearce - American Journal of Physiology …, 1994 - journals.physiology.org
… middle cerebral artery segments from newborn and adult sheep, we … in the affinity of the
agonist for the receptor, as described in the variable … of carotid arteries from fetal sheep. Can. J. …
agonist for the receptor, as described in the variable … of carotid arteries from fetal sheep. Can. J. …
Effect of dopamine on vascular reactivity in near-term lamb carotids: role of the endothelium
DM Angeles, WJ Pearce - Biological Research For Nursing, 2006 - journals.sagepub.com
… -IP(3) coupling in ovine common carotid arteries. American Journal of Physiology and …
5-HT receptor density and agonist affinity in fetal and adult ovine carotid arteries. American …
5-HT receptor density and agonist affinity in fetal and adult ovine carotid arteries. American …
[图书][B] Role of Protein Kinase G in Regulating Vascular Tone in Hypoxic Ovine Cerebral Arteries
RB Thorpe - 2016 - search.proquest.com
… All common carotid arteries used in this study were harvested using sterile techniques from
… In untreated control arteries, agonist affinity (pKa) was significantly greater in fetal than adult …
… In untreated control arteries, agonist affinity (pKa) was significantly greater in fetal than adult …