ERK inhibition attenuates 5-HT-induced contractions in fetal and adult ovine carotid arteries
WJ Pearce, JM Williams, MM Chang… - Archives of physiology …, 2003 - Taylor & Francis
… Using these two inhibitors, the present study has examined the contractile role of ERKs in
contractile responses to 5-HT in ovine carotid arteries, a tissue in which we have previously …
contractile responses to 5-HT in ovine carotid arteries, a tissue in which we have previously …
ERK MAP kinases regulate smooth muscle contraction in ovine uterine artery: effect of pregnancy
… no effect of ERK on Ca 2+ sensitivity (32). Furthermore, in the swine carotid artery, inhibition
of … inhibition of ERK activation, we measured the phenylephrine-induced phosphorylation of …
of … inhibition of ERK activation, we measured the phenylephrine-induced phosphorylation of …
Extracellular signal‐regulated kinases and contractile responses in ovine adult and fetal cerebral arteries
Y Zhao, W Long, L Zhang… - The Journal of …, 2003 - Wiley Online Library
… 2 inhibitors, we added the inhibitor for 20 min prior to administration of agonist. We used the
common carotid arteries … of the MEK inhibitor PD-98059 with that of the ERK inhibitor U-0126 …
common carotid arteries … of the MEK inhibitor PD-98059 with that of the ERK inhibitor U-0126 …
PKC-induced ERK1/2 interactions and downstream effectors in ovine cerebral arteries
Y Zhao, L Zhang, LD Longo - American Journal of …, 2005 - journals.physiology.org
… carotid artery (15) and in rabbit portal vein and femoral artery (37) denied such a role. One
report demonstrated that pharmacological inhibition … the presence of the ERK inhibitor U-0126…
report demonstrated that pharmacological inhibition … the presence of the ERK inhibitor U-0126…
Acclimatization to long-term hypoxia: gene expression in ovine carotid arteries
R Goyal, LD Longo - Physiological Genomics, 2014 - journals.physiology.org
… direction that can be either activating or inhibiting. However, genes can be modulated by …
sheep carotid arteries. A: bar graph of densitometric analysis of phospho-ERK/total (t) ERK …
sheep carotid arteries. A: bar graph of densitometric analysis of phospho-ERK/total (t) ERK …
Maturation and the role of PKC-mediated contractility in ovine cerebral arteries
… sheep uterine artery (56). In the present study, in both fetal and adult cerebral arteries, ERK
inhibition … the swine carotid artery. Am J Physiol Heart Circ Physiol 269: H222–H229, 1995. …
inhibition … the swine carotid artery. Am J Physiol Heart Circ Physiol 269: H222–H229, 1995. …
Pregnancy attenuates uterine artery pressure-dependent vascular tone: role of PKC/ERK pathway
… Several studies (1, 13) have demonstrated that ERK plays a … carotid artery showed that
inhibition of MAPKK (MEK)/ERK … in uterine arteries between nonpregnant and pregnant sheep, …
inhibition of MAPKK (MEK)/ERK … in uterine arteries between nonpregnant and pregnant sheep, …
ERK-mediated uterine artery contraction: role of thick and thin filament regulatory pathways
… carotid artery suggest that ERK might regulate force in … We examined the effects of the MEK
(ERK) inhibitor PD-098059 on … Taken together, we propose that, in sheep uterine artery, PKC …
(ERK) inhibitor PD-098059 on … Taken together, we propose that, in sheep uterine artery, PKC …
Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK
J Wylie-Sears, RA Levine, J Bischoff - Biochemical and biophysical …, 2014 - Elsevier
… phosphorylation of ERK in mitral VEC and carotid artery EC (… inhibited TGFβ1-mediated
EndMT indicated that the ovine … Habashi and colleagues showed Losartan inhibition of AT1 …
EndMT indicated that the ovine … Habashi and colleagues showed Losartan inhibition of AT1 …
Gene expression in sheep carotid arteries: major changes with maturational development
R Goyal, LD Longo - Pediatric research, 2012 - nature.com
… , and its ability to reduce collagen deposition by inhibition of Smad2/3 activation plays a major
role in … Thus, the findings suggest that several components of the MAPK-ERK pathway are …
role in … Thus, the findings suggest that several components of the MAPK-ERK pathway are …