Repair of products of oxidative DNA base damage in human cells

P Jaruga, M Dizdaroglu - Nucleic acids research, 1996 - academic.oup.com
… from cellular DNA. The … of oxidative DNA damage in terms of individual DNA base products.
The approach used may be applicable to studies of repair of oxidative DNA base damage in …

Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repair

TL Scott, S Rangaswamy, CA Wicker… - Antioxidants & redox …, 2014 - liebertpub.com
… Recent Advances: In addition to the notion that oxidative DNA damage causes … cellular
response to oxidative DNA damage during carcinogenesis. Oxidative DNA damage, including 7,8-…

Base-excision repair of oxidative DNA damage

SS David, VL O'Shea, S Kundu - Nature, 2007 - nature.com
… of cellular damage. DNA bases are particularly susceptible to oxidation mediated by ROS 10
… The low redox potential of guanine makes this base particularly vulnerable and leads to a …

Base excision repair of oxidative DNA damage and association with cancer and aging

S Maynard, SH Schurman, C Harboe… - …, 2009 - academic.oup.com
… the association of BER of oxidative DNA damage with aging, … types of oxidative base
modifications in mammalian DNA (64,… DNA (mtDNA) may accumulate more oxidative DNA

Oxidative DNA damage & repair: an introduction

J Cadet, KJA Davies - Free Radical Biology and Medicine, 2017 - Elsevier
… the enzymes that catalyze the oxidation of 5mC, the molecular effects of oxidized 5mC
DNA bases, and finally we discuss the organismal consequences of aberrant 5mC oxidation. …

Oxidative base damage to DNA: specificity of base excision repair enzymes

J Cadet, AG Bourdat, C d'Ham, V Duarte… - … Research/Reviews in …, 2000 - Elsevier
… Modified purine and pyrimidine bases constitute one of the major classes of oxidative DNA
… of transcription-coupled repair of oxidative base damage in yeast and human cells 16, 17. …

Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer

P Jaruga, TH Zastawny, J Skokowski… - FEBS …, 1994 - Wiley Online Library
… four DNA bases with a pattern of modified basesbase damage to DNA in cancerous tissues
as the findings of the present work indicate. Higher levels of typical ‘OH-induced DNA base

Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation.

E Kvam, RM Tyrrell - Carcinogenesis, 1997 - academic.oup.com
… cells almost as much damage as in nongrowing fibroblasts (1.1 per 104 guanine bases after
1200 kJ/m2 UVA) was found. We conclude that oxidative DNA base damage can probably …

Base-excision repair of oxidative DNA damage by DNA glycosylases

M Dizdaroglu - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
… lesions and DNA–protein cross-links. Oxidative DNA damage is mainly repaired by base-excision
repair in living cells with the involvement of DNA glycosylases in the first step and …

Oxidative DNA base damage in renal, hepatic, and pulmonary chromatin of rats after intraperitoneal injection of cobalt (II) acetate

KS Kasprzak, TH Zastawny, SL North… - Chemical research in …, 1994 - ACS Publications
… Some of these bases have been shown previously to be … results imply involvement of oxidative
DNA base damage in Co(… of DNA base derivatives indicative of oxidative DNA damage (6, …