[HTML][HTML] Binding of xanthine oxidase to vascular endothelium: kinetic characterization and oxidative impairment of nitric oxide-dependent signaling
M Houston, A Estevez, P Chumley, M Aslan… - Journal of Biological …, 1999 - ASBMB
… Concentrations of up to 1.5 milliunits/ml xanthine oxidase (XO) (1.1 μg/… Xanthine oxidase
purified from bovine cream bound … Xanthine oxidase-cell binding was not inhibited by serum or …
purified from bovine cream bound … Xanthine oxidase-cell binding was not inhibited by serum or …
Xanthine oxidoreductase in respiratory and cardiovascular disorders
… metabolism, xanthine oxidoreductase (XOR) has been implicated in the development of
tissue oxidative damage in a wide variety of respiratory and cardiovascular disorders such as …
tissue oxidative damage in a wide variety of respiratory and cardiovascular disorders such as …
Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase
U Landmesser, S Spiekermann, S Dikalov, H Tatge… - Circulation, 2002 - Am Heart Assoc
… high xanthine-oxidase activity, suggesting that both reduced ecSOD and increased xanthine
oxidase activity contribute to increased vascular oxidative stress in patients with CHF. This …
oxidase activity contribute to increased vascular oxidative stress in patients with CHF. This …
The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors
N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
… We can understand how high uric acid affects the oxidation, metabolic disorders, and apoptosis
… At the same time, xanthine oxidase inhibitors are also worthy of more research. Related …
… At the same time, xanthine oxidase inhibitors are also worthy of more research. Related …
[HTML][HTML] Xanthine oxidoreductase in atherosclerosis pathogenesis: Not only oxidative stress
MG Battelli, L Polito, A Bolognesi - Atherosclerosis, 2014 - Elsevier
… dysfunction, leading to atherosclerosis, cardiovascular diseases and metabolic syndrome.
XOR activity creates both oxidant and anti-oxidant … in the endothelial dysfunction that is central …
XOR activity creates both oxidant and anti-oxidant … in the endothelial dysfunction that is central …
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction
MA Whidden, JM McClung, DJ Falk… - Journal of applied …, 2009 - journals.physiology.org
… xanthine oxidase (XO) contributes to MV-induced oxidant … -induced diaphragmatic oxidative
stress, contractile dysfunction, and … MV-induced oxidative stress and contractile dysfunction. …
stress, contractile dysfunction, and … MV-induced oxidative stress and contractile dysfunction. …
Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers
S Guthikonda, C Sinkey, T Barenz, WG Haynes - Circulation, 2003 - Am Heart Assoc
… dysfunction, possibly through increased oxidant stress. The enzyme xanthine oxidase produces
oxidative … the hypothesis that xanthine oxidase contributes to endothelial dysfunction in …
oxidative … the hypothesis that xanthine oxidase contributes to endothelial dysfunction in …
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress
J George, AD Struthers - Vascular health and risk management, 2009 - Taylor & Francis
… Allopurinol, a xanthine oxidase inhibitor, has been in clinical … to improve endothelial
dysfunction, reduce oxidative stress … the role of xanthine oxidase in vascular oxidative stress and …
dysfunction, reduce oxidative stress … the role of xanthine oxidase in vascular oxidative stress and …
[HTML][HTML] The impact of xanthine oxidase (XO) on hemolytic diseases
HM Schmidt, EE Kelley, AC Straub - Redox Biology, 2019 - Elsevier
… heme that can mediate endothelial dysfunction directly via redox reactions … , xanthine oxidase
(XO) as the oxidation of hypoxanthine to xanthine and subsequent oxidation of xanthine to …
(XO) as the oxidation of hypoxanthine to xanthine and subsequent oxidation of xanthine to …
Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium‐dependent dilatation with ageing
I Eskurza, ZD Kahn, DR Seals - The Journal of physiology, 2006 - Wiley Online Library
… The results of the present study extend current insight into the mechanisms contributing to
oxidative stress-associated impairment of EDD with ageing in humans. The key new finding …
oxidative stress-associated impairment of EDD with ageing in humans. The key new finding …
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