… oxidative injury. In other experiments, when we measured lung HO expression and indices
of oxidative injury in … had significantly increased markers of oxidative injury prior to hyperoxic …

… In addition to its key role in heme catabolism, HO-1 shows an immediate and adaptive
response to a wide variety of oxidative injuries, suggesting that it plays an important role in the …

The first known human case of heme oxygenase-1 (HO-1) deficiency is presented in this
report. The patient is a six-year-old boy with severe growth retardation. He has been suffering …

… heme oxygenase (HO) -1, the rate-limiting enzyme in heme degradation. Induced HO-1 as
such removes free heme … to tissues from further oxidative injuries. Consistent with this concept…

… and ferritin results in adaptation to LDL-mediated oxidative injury is supported … heme
oxygenase-1 deficient child were prone to oxidative damage arising from heme-mediated oxidation …

… Heme oxygenase consists of two isozymes: an inducible heme oxygenase-1 (HO-1) and
a constitutive heme oxygenase-2 (HO-2; Maines, 1988). Multiple stimuli, including hemolysis, …

… To investigate whether the expression of exogenous heme oxygenase-1 (HO-1) gene within
… cellular protection against oxidative injury and to its inhibitory effect on cellular proliferation. …

… It is well documented that ferrous iron pools that are not stored in ferritin modulate oxidative
injury through generating the hydroxyl radical via the Fenton reaction [25]. In order to …

… Heme oxygenase (HO) activity in tissue adjacent to an intracerebral hematoma may modulate
cellular vulnerability to heme-mediated oxidative injury. … with oxidative injury markers has …

… also play vital roles in the lung's adaptive and/or protective response to oxidative stress.
One such stress-response protein is heme oxygenase-l, HO-l. Since the identification of HO-l in …