Cellular and molecular mechanisms of arrhythmia by oxidative stress

AA Sovari - Cardiology Research and Practice, 2016 - Wiley Online Library
… Other possible arrhythmogenic mechanisms by which CaMKII activation exerts arrhythmic
effects include RyR phosphorylation and activation under oxidative stress [71, 72]. An …

[HTML][HTML] Role of oxidative stress in the genesis of ventricular arrhythmias

A Adameova, AK Shah, NS Dhalla - International Journal of Molecular …, 2020 - mdpi.com
effects of oxidative stress in arrhythmogenesis and to highlight its pivotal contribution to
sudden cardiac death. In addition, it is planned to discuss a concept how oxidative stress, as an …

Oxidative stress on pulmonary vein and left atrium arrhythmogenesis

YK Lin, FZ Lin, YC Chen, CC Cheng, CI Lin… - Circulation …, 2010 - jstage.jst.go.jp
oxidative stress has a direct arrhythmogenic effect on PVs. Previous studies showed that
oxidative stress … + regulatory proteins or cell membrane lipid oxidation status.In addition, H2O2 …

The role of oxidative stress in the pathogenesis and perpetuation of atrial fibrillation

P Korantzopoulos, TM Kolettis, D Galaris… - International journal of …, 2007 - Elsevier
… Experimental and clinical studies indicate that drugs that, among other actions, modulate
oxidative stress exert beneficial effects on AF development, and perhaps on the associated …

Ventricular arrhythmias following exposure of failing hearts to oxidative stress in vitro

F Brigadeau, P Gelé, C Marquie… - Journal of …, 2005 - Wiley Online Library
… that failing heart are more susceptible to the arrhythmogenic effects of H 2 O 2 in vitro. After
14 … H 2 O 2 , which induced toxic effects whereas these effects were not seen in control fibers. …

Oxidative stress: a possible pathogenesis of atrial fibrillation

C Huang, Y Liu, W Xia, Y Tang, H Huang - Medical hypotheses, 2009 - Elsevier
oxidative stress and AF; the levels of the oxidative stress in … of AF; the effects of strategies to
reduce oxidative stress on atrial … fibrosis might contribute to arrhythmogenesis by induction of …

Oxidative stress and inflammation in atrial fibrillation: role in pathogenesis and potential as a therapeutic target

DR Van Wagoner - Journal of cardiovascular pharmacology, 2008 - journals.lww.com
… thereafter, revealed a protective effect on atrial arrhythmogenesis in the setting of heart failure
(… Additional research is needed to clarify the role of these lipids on atrial arrhythmogenesis. …

Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death

AA Sovari, CA Rutledge, EM Jeong… - Circulation …, 2013 - Am Heart Assoc
… Cardiac-restricted elevation of AngII in this model without hypertension, and systolic
dysfunction allowed investigation of the direct arrhythmogenesis effects of AngII in the heart. …

Oxidative stress and atrial fibrillation: finding a missing piece to the puzzle

KC Yang, SC Dudley Jr - Circulation, 2013 - Am Heart Assoc
… of arrhythmogenesis, or our current antioxidant therapies are not targeting the pathogenic
source of oxidative stress … Other effects of AngII and oxidative stress include alterations in Na + …

Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase

JY Youn, J Zhang, Y Zhang, H Chen, D Liu… - Journal of molecular and …, 2013 - Elsevier
… care, as current anti-arrhythmic therapies have limited efficacy and off target effects.
Accumulating evidence has implicated a potential role of oxidative stress in the pathogenesis of AF. …