Oxidative stress, protein modification and Alzheimer disease
A Tramutola, C Lanzillotta, M Perluigi… - Brain research bulletin, 2017 - Elsevier
… The brain is particularly vulnerable to oxidative stress, and accumulation of oxidative …
systems and to eliminate oxidized/misfolded proteins. Perturbation of redox homeostasis may in …
systems and to eliminate oxidized/misfolded proteins. Perturbation of redox homeostasis may in …
… and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress
DA Butterfield, CM Lauderback - Free Radical Biology and Medicine, 2002 - Elsevier
… may be linked by Aβ-induced oxidative stress in AD brain. This review summarizes current
… peroxidation and protein oxidation in AD brain, one potential cause of this oxidative stress, …
… peroxidation and protein oxidation in AD brain, one potential cause of this oxidative stress, …
Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress
RA Floyd, JM Carney - Annals of Neurology: Official Journal of …, 1992 - Wiley Online Library
… Aging in gerbil as well as human brain is also associated with increased oxidative damage.
… brain during ischemia/ reperfusion injury. We also show that oxidative damage to brain …
… brain during ischemia/ reperfusion injury. We also show that oxidative damage to brain …
Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins
DA Butterfield, J Kanski - Mechanisms of ageing and development, 2001 - Elsevier
… Other factors such as apolipoprotein E genotype and mutated presenlin proteins also
may play a role in oxidative stress in AD. While each of these above alterations in AD …
may play a role in oxidative stress in AD. While each of these above alterations in AD …
Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
DA Butterfield, T Reed, SF Newman… - Free Radical Biology and …, 2007 - Elsevier
… sources of oxidative stress in AD brain and the use of redox proteomics to identify oxidatively
modified brain proteins in AD and MCI. New insights into potential oxidative mechanisms …
modified brain proteins in AD and MCI. New insights into potential oxidative mechanisms …
Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain
DA Butterfield - Brain research, 2004 - Elsevier
… the extensive oxidative stress under which the AD brain exists, … to identify specifically oxidized
proteins in AD brain is presented, … that is associated with oxidative stress have emerged. …
proteins in AD brain is presented, … that is associated with oxidative stress have emerged. …
Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics
DA Butterfield, M Perluigi, R Sultana - European journal of pharmacology, 2006 - Elsevier
… peptide metabolism and oxidative stress in Alzheimer's … oxidative stress in Alzheimer's
disease brain are protein carbonyls and 3-nitrotyrosine, which are the markers of protein oxidation…
disease brain are protein carbonyls and 3-nitrotyrosine, which are the markers of protein oxidation…
Oxidative Stress and β-Amyloid Protein in Alzheimer's Disease
Z Cai, B Zhao, A Ratka - Neuromolecular medicine, 2011 - Springer
… within AD brain. Apoptosis takes place in the pathogenesis of AD, and oxidative stress
contributes to … Oxidative stress-induced apoptosis may be a potential factor to Aβ generation. Aβ …
contributes to … Oxidative stress-induced apoptosis may be a potential factor to Aβ generation. Aβ …
Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury
MA Ansari, KN Roberts, SW Scheff - Free Radical Biology and Medicine, 2008 - Elsevier
… , and protein damage may yield a snapshot of oxidative stress. Oxidative/nitrosative stressed
… As a consequence of oxidative stress, both the function and transport of mitochondria to …
… As a consequence of oxidative stress, both the function and transport of mitochondria to …
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
K Dasuri, L Zhang, JN Keller - Free Radical Biology and Medicine, 2013 - Elsevier
… , of oxidative stress in the brain. In this review we discuss the various forms and sources of
oxidative stress in the brain … in detecting the presence of oxidative stress. We then focus the …
oxidative stress in the brain … in detecting the presence of oxidative stress. We then focus the …
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