Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?
TL Crumpton, FJ Seidler, TA Slotkin - Developmental Brain Research, 2000 - Elsevier
… use of chlorpyrifos (CPF) has elicited concern about neurotoxic effects on the fetus and neonate.
CPF targets a number of events specific to brain development, … whether oxidative stress …
CPF targets a number of events specific to brain development, … whether oxidative stress …
Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination
TA Slotkin, CA Oliver, FJ Seidler - Developmental brain research, 2005 - Elsevier
The developmental neurotoxicity of chlorpyrifos (CPF) involves mechanisms other than
inhibition of cholinesterase. In the current study, we examined the ability of CPF to evoke lipid …
inhibition of cholinesterase. In the current study, we examined the ability of CPF to evoke lipid …
Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos
D Qiao, FJ Seidler, TA Slotkin - Toxicology and applied pharmacology, 2005 - Elsevier
… In the current study, we compared the participation of oxidative stress in the developmental
neurotoxicity of nicotine and chlorpyrifos. We selected these two agents for a number of …
neurotoxicity of nicotine and chlorpyrifos. We selected these two agents for a number of …
Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period?
D Qiao, FJ Seidler, S Padilla… - Environmental health …, 2002 - ehp.niehs.nih.gov
… chlorpyrifos (CPF) produced brain cell damage and loss, with resultant abnormalities of synaptic
development. … Is oxidative stress involved in the developmental neurotoxicity of chlorpyri…
development. … Is oxidative stress involved in the developmental neurotoxicity of chlorpyri…
Chlorpyrifos induces oxidative stress in oligodendrocyte progenitor cells
MD Saulsbury, SO Heyliger, K Wang, DJ Johnson - Toxicology, 2009 - Elsevier
… Due to the fact that the organophosphates; particularly chlorpyrifos, causes oxidative
damage in the central nervous system, our laboratory decided to investigate its effects on …
damage in the central nervous system, our laboratory decided to investigate its effects on …
Developmental neurotoxicity of organophosphates: a case study of chlorpyrifos
TA Slotkin - Toxicology of organophosphate & carbamate …, 2006 - Elsevier
… developmental neurotoxicant. A case study of the developmental neurotoxicity of chlorpyrifos
… and misleading in evaluating the developmental neurotoxicity of chlorpyrifos, and likely for …
… and misleading in evaluating the developmental neurotoxicity of chlorpyrifos, and likely for …
Developmental neurotoxicity of chlorpyrifos: targeting glial cells
SJ Garcia, FJ Seidler, TA Slotkin - Environmental toxicology and …, 2005 - Elsevier
… Because we were still able to detect enhanced ROS generation and enhanced sensitivity
to oxidative stressors, CPF clearly has the potential to enhance oxidative stress even in …
to oxidative stressors, CPF clearly has the potential to enhance oxidative stress even in …
The toxicity of chlorpyrifos on the early life stage of zebrafish: a survey on the endpoints at development, locomotor behavior, oxidative stress and immunotoxicity
Y Jin, Z Liu, T Peng, Z Fu - Fish & shellfish immunology, 2015 - Elsevier
… evaluation of the developmental neurotoxicity potential of … to neurotoxicity, innate immune
system and oxidative stress have … on development, locomotor behavior, oxidative stress and …
system and oxidative stress have … on development, locomotor behavior, oxidative stress and …
Acute exposure to chlorpyrifos caused NADPH oxidase mediated oxidative stress and neurotoxicity in a striatal cell model of Huntington's disease
GA Dominah, RA McMinimy, S Kallon, GF Kwakye - Neurotoxicology, 2017 - Elsevier
… Thus, deficits in ascorbic acid uptake may contribute to the oxidative stress and neurotoxicity
that we report in this study. Though mutant HD cells may be less efficient at ascorbic acid …
that we report in this study. Though mutant HD cells may be less efficient at ascorbic acid …
Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells
TA Slotkin, FJ Seidler - Environmental Health Perspectives, 2009 - ehp.niehs.nih.gov
… Critical periods for the role of oxidative stress in the developmental neurotoxicity of
chlorpyrifos and terbutaline, alone or in combination. Dev Brain Res 157:172-180 https://www.ncbi.…
chlorpyrifos and terbutaline, alone or in combination. Dev Brain Res 157:172-180 https://www.ncbi.…
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