Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

JL Evans, ID Goldfine, BA Maddux… - Endocrine …, 2002 - academic.oup.com
… In this review, we now propose that oxidative stress induced by … the degree of oxidative stress
and activation of stress-sensitive … of the treatment program for patients with type 2 diabetes. …

Mechanism of generation of oxidative stress and pathophysiology of type 2 diabetes mellitus: how are they interlinked?

K Rehman, MSH Akash - Journal of cellular biochemistry, 2017 - Wiley Online Library
… the notion that oxidative stress is strongly correlated with the … revealed that ROS and oxidative
stress are among the main … of oxidative stress generation, correlation of oxidative stress, …

Oxidative stress and the JNK pathway are involved in the development of type 1 and type 2 diabetes

H Kaneto, T Matsuoka, N Katakami… - Current molecular …, 2007 - ingentaconnect.com
… also induced the nuclear localization of Foxo1, but in contrast, suppression of the JNK pathway
reduced the oxidative stressinduced … In addition, oxidative stress or activation of the JNK …

Oxidative stress in type 1 diabetes

K Haskins, B Bradley, K Powers… - Annals of the New …, 2003 - Wiley Online Library
oxidative stress on pathogenesis and complications of type 1 diabetes in the NOD mouse
model. Our studies have shown that damage caused by oxidative stress … of oxidative stress in …

The AT1-Type Angiotensin Receptor in Oxidative Stress and Atherogenesis: Part I: Oxidative Stress and Atherogenesis

G Nickenig, DG Harrison - Circulation, 2002 - Am Heart Assoc
… AT 1 receptor–induced oxidative stress and atherosclerosis. AT 1 receptor activation leads
to the release of reactive oxygen species in various vascular cells. Oxidative stress is in turn …

[HTML][HTML] NRF2 oxidative stress induced by heavy metals is cell type dependent

SO Simmons, CY Fan, K Yeoman… - Current chemical …, 2011 - ncbi.nlm.nih.gov
… cell type. We conclude that cells differ dramatically in either their ability to mount an effective
oxidative stress … These findings suggest that the properties of Nrf2 activation are cell-type

[PDF][PDF] Hyperglycemia induced oxidative stress in type-1 and type-2 diabetic patients with and without nephropathy

GS Dave, K Kalia - Cell Mol Biol (Noisy-le-grand), 2007 - researchgate.net
… with hyperglycemia, hyperlipoproteinaemia and oxidative stress at cellular level. … -oxidative
system of cells and hyperglycemia induced reactive oxygen species (ROS) in type-1 and type-…

Effects of different types of oxidative stress in RPE cells

L Lu, SF Hackett, A Mincey, H Lai… - Journal of cellular …, 2006 - Wiley Online Library
… damage from H 2 O 2 or hyperoxia, but not that induced by paraquat. We conclude that
exposure to different types of oxidative stress results in different patterns of accrual of oxidative

Oxidative stress and the etiology of insulin resistance and type 2 diabetes

EJ Henriksen, MK Diamond-Stanic… - Free Radical Biology and …, 2011 - Elsevier
… ) or overt type 2 diabetes, … , oxidative stress, involved in the multifactorial etiology of insulin
resistance of glucose transport activity in skeletal muscle. The discussion of oxidative stress in …

[HTML][HTML] The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication

YC Chang, LM Chuang - American journal of translational …, 2010 - ncbi.nlm.nih.gov
type 2 diabetes and increasing longevity. Increased production of reactive oxygen species
(ROS), resulting in oxidative stress… mechanism by which oxidative stress provoked by nutrient …